Protein Alignment CarT and Slc22a20

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001381833.1
• Gene: Slc22a20 / 293686
• RGDID: 1311460
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 563
• Identity: 166/563 - (29%)
• Similarity: 257/563 - (45%)
• Gaps: 86/563 - (15%)

  Fly    38 DLLPTIGEFGKYQKLLVFGICLPACIPCGFCA---FNQLFMADTPDDY----------------- 82
            |||..:|..|::|  ||:...|  .:|||..|   |.|.|.|..|..:
  Rat     5 DLLDALGGVGRFQ--LVYTALL--LLPCGLLACHTFLQNFTAAAPPHHCQHPANYTEATTNDSGA 65

  Fly    83 WCRIPELLDLPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLI 147
            |.|    ..:||.|.   .:|:          .|..|           .|.....:|||.|...:
  Rat    66 WLR----ATIPLNQH---GVPE----------PCQRY-----------TEPQWALLEPNTSSHGV 102

  Fly   148 K---CPQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSY 209
            .   |..||.|:.|:..|:||:::||||:......:..:...:|..||..|||.|.||.||:...
  Rat   103 ATEGCKDGWVYDRSIFPSTIVMEWDLVCEARTLRDLAQSIYMSGVLVGAALFGSLADRLGRKAPL 167

  Fly   210 FVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGE----NYRSFVTVMT 270
            ......|.....:|:....|..:...|.::|:|...:    .:.||.||.|    ..|:...::.
  Rat   168 VWSYLQLAVSGAVTAYVGSFSAYCIFRFLMGMTFSGI----ILNSLSLVVEWMPTRGRTVAGILL 228

  Fly   271 CTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERM 335
            ...:|.|.::|:||.||.|.|..|.:..|.||..:|||.:.:|||.||||:.|:.::|::.|.::
  Rat   229 GFSFTLGQLILAGVAYLIRPWRWLQFAVSAPFLVFFLYSWWLPESSRWLLLHGKAQQAVQNLRKV 293

  Fly   336 AKVNGREFPEAVHLKLE----------AQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITL 390
            |.:|||: .|...|.:|          |.:|...           .:.||.|||.:|..|..:.:
  Rat   294 AMMNGRK-AEGERLTIEVVSSYIQNEFASVRTSN-----------SILDLFRTPGIRKVTCCLMM 346

  Fly   391 SWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVAC 455
            .||:|...|.||:......|.:.|:...|..::::|:.|.....|...|||..:|..::|.|:..
  Rat   347 VWFSNSVAYYGLAMDLQKFGLSIYLVQALFGIIDIPAMLVATTTMIYVGRRATVSSFLVLAGLMV 411

  Fly   456 VITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPF 520
            :..:.:|:|......|...:.|..|::||:.:|.|.||||||::|.:|:|.:|....||.:..|.
  Rat   412 IANMFVPEDLQTLRTVQAALGKGCLASSFICVYLFTGELYPTEIRQMGMGFASVNARLGGLAAPL 476

  Fly   521 ITYLGKDNLKLPLVIMGFLSMLGGMTGL-RLPETLHHRLPQTI 562
            ||.||:.:..||.|..|..|:|.||..: .|.||.:..|.:||
  Rat   477 ITTLGEISPVLPPVSFGATSVLAGMAVICFLTETRNVPLVETI 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	128/413 (31%)
		xylE	<306..>342	CDD:182225	16/35 (46%)
Slc22a20	NP_001381833.1	MFS_SLC22A6_OAT1_like	103..508	CDD:341004	129/420 (31%)