Protein Alignment CarT and fnx2

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_596093.1
• Gene: fnx2 / 2541016
• PomBaseID: SPBC3E7.06C
• Length: 577
• Species: Schizosaccharomyces pombe
• Alignment Length: 578
• Identity: 108/578 - (18%)
• Similarity: 178/578 - (30%)
• Gaps: 209/578 - (36%)

  Fly   133 DDLTTMEPNASWPLIK--------------CPQGWEYNTSVVWSS-------IVIDFDLVCDQDI 176
            |.|:::..|:|:..||              .|:..|.:.|||.:|       .......|....:
pombe    27 DSLSSLNGNSSYDSIKDSSKNNKDVAEVNEYPRRPESSVSVVSNSPHRQDAATTNTVSTVSVSKV 91

  Fly   177 YPT----IGLAAL-NT---------GGPVGVY-------------------LFGLLNDRGGRRLS 208
            .|.    :.|||| ||         |...|.:                   |||...|..||:.:
pombe    92 LPALLLGVVLAALDNTIVASTYTKIGAEFGKFSQVSWTATAYMISCTAFQPLFGKFCDIYGRKKT 156

  Fly   209 YFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTF 273
            ..........|..:...|:..|....:|.|.|:....:.....|:..::|....|.....:...|
pombe   157 LLAAYCVFGIGCFLCGTSRSLWQLVAARAIAGIGGGGMNSTVSILMSDIVPLKQRGTYQGIINVF 221

  Fly   274 YTSGIML---LSGVTYLERDWVRLSYITSLPFYAY-FLYMFVMPESPRWLLMRGRLEEALKILER 334
            :..|..|   :.|....:..| |:.::..:|..|. ||.::..
pombe   222 FAIGSSLGGPVGGYFADQYTW-RIGFLIQVPLIAIAFLCVYFT---------------------- 263

  Fly   335 MAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITL-----SWFA 394
                  ...|...|:....:.|:..||         ||  :.....:...|...||     .|
pombe   264 ------LNLPHHNHVSFMTRFRKIDLK---------GL--ILLIIGVTTMTCAFTLGGNVREW-- 309

  Fly   395 NETVYLGLSYYGPALGTNQYVSF-FLSAVVE---------------LPSYLCCWYFMDT---WGR 440
            |:.|.:.|.    ...:..|:|| ::.|.|.               |.||||.::....   |..
pombe   310 NDPVVISLL----IASSISYLSFVYVEAFVAFEPLAPMDVLTERTCLSSYLCNFFHSVANFGWIY 370

  Fly   441 RWPL------------------------SLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLS 481
            ..||                        ||..:|||.    .:.|..:....|:..|....  ::
pombe   371 GMPLFFQSIKNEGAEKSGIRLIPMIIGSSLGSLLGGA----VISLTGNYKKITVGSYFFGS--VA 429

  Fly   482 ASFLI------------IYPFAGELYPTQVRGIGIGASSYIGGLGLIGIP--------FITYLGK 526
            |.|::            :|||:|.|      |.||..::.:..: :...|        ..:||.:
pombe   430 ALFMLRYGYSNFNWEYAVYPFSGGL------GNGIAVTTTLVAI-IHASPSAFQASAIATSYLFR 487

  Fly   527 DNLKLPLVIMGF---LSMLGGMTGLRL--------PETLH---------HRLPQTIEE 564
            .|    ..::|.   .|::..:.|::|        .|.||         ||||:.|.:
pombe   488 SN----GCVLGVSISSSIVQTVLGIKLRKSLDFDVDELLHHLRKDISYVHRLPEEIRQ 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	93/521 (18%)
		xylE	<306..>342	CDD:182225	2/35 (6%)
fnx2	NP_596093.1	MFS_Azr1_MDR_like	105..497	CDD:341045	79/454 (17%)