Protein Alignment CarT and Slc22a15

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 638
• Identity: 168/638 - (26%)
• Similarity: 268/638 - (42%)
• Gaps: 133/638 - (20%)

  Fly    30 VDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMAD----------TPDDYWC 84
            |:|||.      .:||.|.||..|.|.:.:          ..||::|.          ||..:|
Mouse     3 VEEAFQ------AVGEMGLYQMYLCFLLAV----------LLQLYVATEAILIALIGATPAYHW- 50

  Fly    85 RIPELLDLPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKC 149
               ::.||         :|.:..:::.: .|...:| :|. |..:|.|........|:
Mouse    51 ---DMADL---------LPNQSHSNQTL-GKGQAFG-DWL-LTANGSEIHKHVHFSNS------- 93

  Fly   150 PQGWEYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLA 214
                       ::||..::.|:.::....:...::..:|..|||..||.|:||.|||..|....|
Mouse    94 -----------FTSIASEWFLIANRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFA 147

  Fly   215 TLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIM 279
            ..:..::....|..:..:|.:|.:||:....:..:.|::..|.||..|.:....:...|:..||.
Mouse   148 LDILFAVANGFSPSYEFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVGIA 212

  Fly   280 LLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFP 344
            ..:.:.|..|.|..|:.:.:|.....||....:|||||||..:|||.||.:.|..:||
Mouse   213 QYALLGYFIRSWRTLAVLVNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAK------- 270

  Fly   345 EAVHLKLEAQIRRDKLK--------KQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLG 401
                       |..|||        ..:...|.....||.|...:...|:::...||....||.|
Mouse   271 -----------RNRKLKCTFSLTHPANRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYG 324

  Fly   402 LSYYGPALGTNQYVSFFLSAVVELPSY-LCCWYFMDTW-GRRWPLSLSMILGGVACVITVMLPDD 464
            |:.....||.:.|.:..||.::|:||| ||.:.....| ||:..|:..:.|||:||:|.:.||:.
Mouse   325 LTLSAGDLGGSIYANLALSGLIEIPSYPLCIYLINQRWFGRKRTLAAFLCLGGLACLIVMFLPEK 389

  Fly   465 ------AVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY 523
                  ||..:..|.|:.|..:||:|.|:|.:..|||||.:|.:|:||.|....:|.|..||:..
Mouse   390 KDTGVFAVVNSHSLSLLGKLTISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPS 454

  Fly   524 LGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEE---------GEEFGKNWQFKDCCR 579
            |.:....||.::.|...:..|:..|.|||||:..|.:|..:         |||
Mouse   455 LKEVQWSLPFIVFGATGLTSGLLSLLLPETLNSPLLETFSDLQMYSYRRLGEE------------ 507

  Fly   580 CAQKPEILSQPASYENLDVLAGSSTNASEVELELRDSRRVREPAPRIDERTPL 632
             |...:.|..|...:.:       ::.||.|.|..|:          ||.|.:
Mouse   508 -ALSLQTLDPPQPLDKV-------SSESEEEEEFYDA----------DEETQM 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	120/414 (29%)
		xylE	<306..>342	CDD:182225	17/35 (49%)
Slc22a15	NP_001034460.2	MFS_SLC22A15	71..469	CDD:340935	123/435 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544		10/47 (21%)