Protein Alignment CarT and Slc22a26

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_017173677.1
• Gene: Slc22a26 / 236149
• MGIID: 2385316
• Length: 553
• Species: Mus musculus
• Alignment Length: 554
• Identity: 141/554 - (25%)
• Similarity: 257/554 - (46%)
• Gaps: 51/554 - (9%)

  Fly    38 DLLPTIGEFGKYQ--KLLVFGIC----LPACIPCGFCAFN-------QLFMADTPDDYWCRIPEL 89
            |||..:|..|::|  ::....||    :|..|...|.|.|       .:...||..:....|
Mouse     5 DLLNLVGSHGRFQILQMAFLLICNVITMPHVILENFTAANLGHRCWVHIIDNDTNSNNNSGI--- 66

  Fly    90 LDLPLEQRKSLSIPKELDNDELVYSKCYTY-GVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGW 153
                |.|...|.|...||:: |...||..: ...|..|..:|...::|  ||:..    .|..||
Mouse    67 ----LSQDDLLRISIPLDSN-LRPEKCRRFVQPQWHLLQFNGSFSNMT--EPDTE----PCMDGW 120

  Fly   154 EYNTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLA 218
            .|:.....|:.|.:::|||......::.......|...|.::.|.|:|:.||:|.:...|..:..
Mouse   121 VYDQRTFLSTTVTEWNLVCGSQELNSVAKFIFLIGVLAGHFVGGHLSDKFGRKLLFRCALLQMAI 185

  Fly   219 GSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSG 283
            ....|:|:..|:.:...|.:.||.|..:.....::.||......::.||.::.:.:..|.::|:|
Mouse   186 TGTCTALAPTFFIYCLLRFLTGLCIIPINTNSVLLMLEWTSPKTQALVTTLSMSSHHFGGLILAG 250

  Fly   284 VTYLERDWVRLSYITSLPFYAYFLYMFVMP------ESPRWLLMRGRLEEALKILERMAKVNG-R 341
            :.:..::|..|....|:|     :::.::|      ||.|||::..:.::||:.|.::|..|| :
Mouse   251 LAFAFQNWHHLQLAISVP-----IFVLLIPTSRWLTESARWLIVTNKPQKALQELRKVASKNGIK 310

  Fly   342 EFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYG 406
            ...:.:.:::...|.:|::...:.|.:   |.||...||:|.:..|:.|..|...:..:|::...
Mouse   311 NSEDVLTMEVVRTIMKDEIAIPRTKPS---LRDLFHMPNLRKRLCLLCLLRFLQISPTVGINMNL 372

  Fly   407 PALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLV 471
            ..|..|.:::..|::...:|:.....:.::..|||....|..:|.|:..:..|.:|.:.  :||:
Mouse   373 QHLKGNVFLTQSLTSAFSIPATALGGFLLNYIGRRISQLLPCLLFGIFLLSIVSVPQEM--QTLL 435

  Fly   472 LYLVSKALLSASFLIIYP----FAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLP 532
            :.|::  |...|..:||.    ::.||.||.:|...:|.....||:|....|.|..|...:..||
Mouse   436 VVLIT--LAGGSSAMIYNSNVLYSSELMPTVIRATALGVIGICGGVGAALSPLIMILTLYSASLP 498

  Fly   533 LVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGE 566
            .:|.|.||:|||:..|.||||.:..||.:|::.|
Mouse   499 WIIYGVLSILGGLLPLILPETKNQPLPDSIQDVE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	101/409 (25%)
		xylE	<306..>342	CDD:182225	12/42 (29%)
Slc22a26	XP_017173677.1	MFS	109..506	CDD:475125	99/414 (24%)