Protein Alignment CarT and Slc22a5

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 569
• Identity: 178/569 - (31%)
• Similarity: 289/569 - (50%)
• Gaps: 27/569 - (4%)

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99
            |.|::...:||:|.:|:|:.| :...:.||.||...:.:|:|.|| ::.|.:|..::|....|..
Mouse     3 DYDEVTAFLGEWGPFQRLIFF-LLSASIIPNGFNGMSIVFLAGTP-EHRCLVPHTVNLSSAWRNH 65

  Fly   100 LSIPKELDNDELVYSKCYTYGV----NWTQL-LESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159
             |||.|..:...|..||..|.:    |:::| ||.|.:.||..:|..:      |..||||:..|
Mouse    66 -SIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQES------CLDGWEYDKDV 123

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTS 224
            ..|:||.::||||..|....:..:....|..:|.::.|.|:||.||:...|:.:......|.:..
Mouse   124 FLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQTGFSFLQV 188

  Fly   225 LSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR-SFVTVMTCTFYTSGIMLLSGVTYLE 288
            .|.:|..:....|:||:...:.|...|::..|::.::.| .|.|:..|.||..|.|:|....|..
Mouse   189 FSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFMVLPLFAYFI 253

  Fly   289 RDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEA 353
            |||..|....::|........:.:|||||||:.:||::||..|:.:.||:||...|..:....|.
Mouse   254 RDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAPSTIFDPSEL 318

  Fly   354 QIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFF 418
            |    .|...|.::.::  .||.||.|:|:.||:..:.|......|.|||...|.|..:.||:.|
Mouse   319 Q----DLNSTKPQLHHI--YDLIRTRNIRVITIMSIILWLTISVGYFGLSLDTPNLHGDIYVNCF 377

  Fly   419 LSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSAS 483
            |.|.||:|:|:..|..:....||:.:|.::.|||...:...::|.:....:..|.:|.|..::::
Mouse   378 LLAAVEVPAYVLAWLLLQYLPRRYSISAALFLGGSVLLFMQLVPSELFYLSTALVMVGKFGITSA 442

  Fly   484 FLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGL 548
            :.::|.:..|||||.||.:|:|.||....||.|..|:..|||..:..||.::||.|::|..:..|
Mouse   443 YSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGAYDRFLPYILMGSLTILTAILTL 507

  Fly   549 RLPETLHHRLPQTIEEGEEFG--KNWQFKDCCRC----AQKPEILSQPA 591
            ..||:....||.||::.....  |.||.:...|.    .:.|.:|...|
Mouse   508 FFPESFGVPLPDTIDQMLRVKGIKQWQIQSQTRMQKDGEESPTVLKSTA 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	128/399 (32%)
		xylE	<306..>342	CDD:182225	16/35 (46%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	167/522 (32%)