Protein Alignment CarT and Slc22a8

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_112471.3
• Gene: Slc22a8 / 19879
• MGIID: 1336187
• Length: 537
• Species: Mus musculus
• Alignment Length: 582
• Identity: 166/582 - (28%)
• Similarity: 264/582 - (45%)
• Gaps: 98/582 - (16%)

  Fly    38 DLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFN--QLFMADTPDDYWCRIP-----ELLDLPLE 95
            ::|..:|..|.:|.|.|..:.||.   .|....|  |:|.|.|||.: ||.|     |...|||.
Mouse     5 EILDRVGSMGPFQYLHVTLLALPI---LGIANHNLLQIFTATTPDHH-CRPPPNASLEPWVLPLG 65

  Fly    96 QRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWP------LIKCPQGWE 154
            ....   |:          ||    :.:..|             ||||.|      ...|..||.
Mouse    66 PNGK---PE----------KC----LRFVHL-------------PNASLPNDTQGATEPCLDGWI 100

  Fly   155 YNTSVVWSSIVIDFDLVCD----QDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRR----LSYFV 211
            ||::  ..:||.::||||.    :::..::.:|.:..||||    ||.|:||.||:    .||.:
Mouse   101 YNST--RDTIVTEWDLVCGSNKLKEMAQSVFMAGILVGGPV----FGELSDRFGRKPILTWSYLL 159

  Fly   212 CLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYR--SFVTVMTCTFY 274
                |.|.....:.|.....:...|.:.|.:|..:.....|:::|.|..:.|  |..|:..|  |
Mouse   160 ----LAASGSSAAFSPSLTVYMIFRFLCGCSISGISLSTIILNVEWVPTSTRAISSTTIGYC--Y 218

  Fly   275 TSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVN 339
            |.|..:|.|:.|....|..|....|..|:.:.|..:.:|||.|||::.|:..:|||.|:|:|..|
Mouse   219 TIGQFILPGLAYAVPQWRWLQLSVSAAFFIFSLLSWWVPESIRWLVLSGKFSKALKTLQRVATFN 283

  Fly   340 GRE------FPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETV 398
            |::      ..|.:...|:..|...|:|        .||:||.|...:|..|..::|:|||.
Mouse   284 GKKEEGEKLTVEELKFNLQKDITSAKVK--------YGLSDLFRVSILRRVTFCLSLAWFAT--- 337

  Fly   399 YLGLSYYGPALGTNQY-VSFFLSAV----VELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVIT 458
              |.:||..|:|..:: |:.::..:    |::|:.......:...|||......:||.|||.:..
Mouse   338 --GFAYYSLAMGVEEFGVNIYILQIIFGGVDIPAKFITILSISYLGRRITQGFLLILAGVAILAL 400

  Fly   459 VMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY 523
            :.:..:.......|.:..|..||.||..::.:..|||||.:|..|:|.|:....:|.:..|.:..
Mouse   401 IFVSSEMQLLRTALAVFGKGCLSGSFSCLFLYTSELYPTVLRQTGMGISNIWARVGSMIAPLVKI 465

  Fly   524 LGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCCRCAQKPE 585
            .|:....:|.||.|.:::|||.....|.|||:..||:|||:.::    | ::...:..|:||
Mouse   466 TGELQPFIPNVIFGTMTLLGGSAAFFLLETLNRPLPETIEDIQD----W-YQQTKKTKQEPE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	120/419 (29%)
		xylE	<306..>342	CDD:182225	16/35 (46%)
Slc22a8	NP_112471.3	2A0119	11..503	CDD:273328	158/550 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..537		3/10 (30%)