Protein Alignment CarT and K05F1.6

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001342018.1
• Gene: K05F1.6 / 173977
• WormBaseID: WBGene00019408
• Length: 858
• Species: Caenorhabditis elegans
• Alignment Length: 713
• Identity: 165/713 - (23%)
• Similarity: 291/713 - (40%)
• Gaps: 142/713 - (19%)

  Fly    17 ELRQRH--------------KPESQPSVDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPCGF 67
            |:|::|              :.|.:|:  :..|.:.:|..||.. ::.::.::.:.....||...
 Worm   171 EIREQHQKVQQIYRDVNKKERKEGKPT--DPIDFEGILNIIGGC-RWWQIWIYVLIALQQIPHAM 232

  Fly    68 CAFNQLFMADTPDDYWCRIPELLDL-------------PLEQRKSLSIPKELDNDELVYSK--CY 117
            ...|.::|...| ::.|.:|...|.             .::..|::|......|.:..|.:  ||
 Worm   233 FNLNVVYMMYDP-EFQCMVPGFNDTNDTTISSHGPYLWGVDDIKNISFVFPNANSDGAYQRDSCY 296

  Fly   118 TYGVNWTQLLESGEED-------DLTTMEPNASW----PLIKCPQGWEYNTSVVWSSIVIDFDLV 171
            .|        |..||.       .|.|....| |    |..|| |.:.:...|:..:||.||:||
 Worm   297 FY--------ERSEERYRQLRRMPLETAMSEA-WKDVAPKKKC-QAYHFEKDVMVETIVTDFNLV 351

  Fly   172 CDQ-------DIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSL---- 225
            ||.       .::.:||..       :|..|.|:.:|:.||:       .|::...:::|:
 Worm   352 CDSWFAKGHAHMFYSIGYL-------LGCVLGGIASDKIGRK-------PTIIGFGILSSMLGVF 402

  Fly   226 --SKDFW-TWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYL 287
              ..|:: .:...|::..:...|.....:.:.:|:.|..||:.|..|....:..|..||:.:.||
 Worm   403 LPFNDYYPMFLLIRLLSAICNEAADLAAYTLCMEITGTKYRAMVGSMLQAPWALGYALLALIAYL 467

  Fly   288 ERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHL--- 349
            .:.|..:..|.:...:...:::..:|||||||:::.|:.||.:::.:..    ||.|...::
 Worm   468 TKSWKTIQVIAAGLHFMSIIFICSIPESPRWLMVQNRVSEAEEVIRKAC----REPPFPFNMCTT 528

  Fly   350 --------KLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYY- 405
                    .||....|:: |..||....:|..||.....:|.:||.:.:.:.|...||.||...
 Worm   529 SKCGNLPSDLELVSHRER-KLNKKNGGKIGFLDLFTMKELRYRTISVCIVFMATALVYYGLVMAL 592

  Fly   406 --GPALGTNQYVSFF-----LSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPD 463
              ..|.|...:..:|     ::..:|:|:...|.:.|.. ||:..|.|::|..|:..::.::
 Worm   593 SDQSAPGRTLFTGYFHLNNGIAGAIEIPTLFACVWMMQL-GRKKALMLTLITSGLFIIVAML--- 653

  Fly   464 DAVDETLVLYLV----SKALLSASFLIIYPFAGELYPTQVRG-----------IGIGASSYIGGL 513
            ..|....:|.|.    .|..:..:|.|:|.|..|||||.||.           .|.|.||||..|
 Worm   654 SMVSGHYMLALAFMYFGKIAVQGAFNILYIFTSELYPTVVRNTAVGVTSMVARFGSGLSSYIALL 718

  Fly   514 GLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFKDCC 578
            ..|.:|.:          |::|....|:..||....||||....||:|:::...|.:..:..:|
 Worm   719 SNISLPIV----------PMIIFAVFSLFAGMLVFVLPETSEKPLPETLDDAINFLEPTKQVNC- 772

  Fly   579 RCAQKPEILSQPASYENLDVLAGSSTN--ASEVELELRDS---RRVREPAPRIDERTPLDTTA 636
             ...:..:.......:::.:....|||  |....|..|.|   ||:.|.|..|..|....|.:
 Worm   773 -MMGRFGVFGHQKMTKSISLTENPSTNDIADLKPLSRRSSAITRRMTERASVIYSRNASRTNS 834

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	107/446 (24%)
		xylE	<306..>342	CDD:182225	10/35 (29%)
K05F1.6	NP_001342018.1	MFS_SLC22	333..746	CDD:340875	107/445 (24%)