Protein Alignment CarT and LOC1277194

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_316638.4
• Gene: LOC1277194 / 1277194
• VectorBaseID: AGAMI1_010343
• Length: 720
• Species: Anopheles gambiae
• Alignment Length: 668
• Identity: 215/668 - (32%)
• Similarity: 333/668 - (49%)
• Gaps: 64/668 - (9%)

  Fly     5 EDNDGDEYDELSELRQRHKPESQPSV----------------DEAFDLDDLLPTIGEFGKYQKLL 53
            :||..|      |||:..|..:|..|                ....|.|||||.:||||:|||:|
Mosquito    62 KDNHED------ELRKETKNSNQHGVVMVATNGASTGAAVAEKPVVDFDDLLPHVGEFGRYQKIL 120

  Fly    54 VFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSLSIP------KELD----- 107
             |.:.:|......|..|:|:|:...|:::||.:|||..|.:|:|::|:||      .|||
Mosquito   121 -FLLMIPFAFFVAFVYFSQIFITLVPEEHWCYVPELQHLSVEERRALAIPVDESYGAELDAGVVG 184

  Fly   108 --NDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYN-TSVVWSSIVIDFD 169
              :..:.||||..|.||:|::|    .:::...:|  |||...|..||||| |.|.:.:...||:
Mosquito   185 DGSPPISYSKCTMYAVNFTEVL----ANNIRKADP--SWPTQPCRHGWEYNFTDVPYQTAATDFE 243

  Fly   170 LVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAG 234
            .|||....||:..:....|..||..|||.:.||.||..:...|.....|..:.|:...:||.::.
Mosquito   244 WVCDHAYLPTLAQSIFFLGAIVGGLLFGWIADRYGRIPALAGCNLIGFAAGVATAFVGNFWQFSL 308

  Fly   235 SRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMT-CTFYTSGIMLLSGVTYLERDWVRLSYIT 298
            .|.:||......:.:.:|:.||.||..:|:||..|: ..|:|:....|..:.|...||...:.:|
Mosquito   309 CRFLVGFAFDNCFTMMYILVLEYVGPKWRTFVANMSIALFFTTASCALPWIAYYLADWKTFAIVT 373

  Fly   299 SLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQ 363
            |.|.....|...|:|||.|||:.:|::::|:.||::...:|.:.....|:.:......|  |:::
Mosquito   374 SAPLALAILTPLVVPESARWLVSQGKIDKAIGILKKFETINKKTIDAKVYQEFSDSCVR--LQEE 436

  Fly   364 KKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSY 428
            :...:|..:.||.:||.:|..|||:.:.|.|...|:.|......:||.:.:.:|.::|..|||:.
Mosquito   437 EAANSNYSVLDLFKTPRLRNITILLIVIWMAISLVFDGHVRNVGSLGLDLFFTFTVAAATELPAD 501

  Fly   429 LCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGE 493
            ......:|.|||||....:|:..|:..:...|:|..|...||.  ::.:..::.|:.|...:|.|
Mosquito   502 TFLTLTLDRWGRRWLACGTMVASGLFSLFATMVPMGAYSATLA--ILGRFSVNISYNIGLQYAAE 564

  Fly   494 LYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRL 558
            |.||.||..|:.....:|.:..|..||:.||...:..|||:::|.|.:.||:..|.|||||.|.|
Mosquito   565 LLPTVVRAQGVAFIHIMGYVASIVAPFVVYLANISPSLPLIVLGILGIFGGLLSLLLPETLGHDL 629

  Fly   559 PQTIEEGEEFG---KNWQF-------KDCCRCAQKP-EILSQPASYENLDVLAGSSTNASEVELE 612
            |||:.:|||||   |.|.|       .|...|...| |..::..|..::    |:|..|| ...|
Mosquito   630 PQTLADGEEFGRGQKIWDFPCLTKKVDDDDTCDDLPVERFTRATSKTSI----GASLRAS-TRGE 689

  Fly   613 LRDSRRVREPAPRIDERT 630
            ||.|...|....|:..|:
Mosquito   690 LRSSMLNRSIRSRVSVRS 707

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	123/400 (31%)
		xylE	<306..>342	CDD:182225	13/35 (37%)
LOC1277194	XP_316638.4	2A0119	111..632	CDD:273328	174/531 (33%)