Protein Alignment CarT and Slc22a13

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_598741.2
• Gene: Slc22a13 / 102570
• MGIID: 2143107
• Length: 551
• Species: Mus musculus
• Alignment Length: 546
• Identity: 155/546 - (28%)
• Similarity: 259/546 - (47%)
• Gaps: 53/546 - (9%)

  Fly    39 LLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIP----ELLDLPLEQRKS 99
            ::..:|:||::|..|...:.:|..: ..|..|.|:||. ..:.:.|.:.    ...:|...::.:
Mouse     7 VMAEVGDFGRFQVRLTILMGIPNFL-AAFFIFGQVFMV-LDEAHHCSVSWVKNHTFNLSAAEQLA 69

  Fly   100 LSIPKELDNDELVYSKCYTYGVNWTQLL-----ESGEEDDLTTMEPNASWPLIKCPQGWEYNTSV 159
            :|||    ||        |.|...:.|:     :|...:|:.:...|.:.   .|..||:|..:.
Mouse    70 ISIP----ND--------TAGRPESCLMFRPPPDSASLEDILSHRFNETQ---ACDSGWDYPENR 119

  Fly   160 VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAG--SLM 222
            . .|:..:||||||:........:....|..||..:||.:.|..|||.|  :.:..||:|  |:.
Mouse   120 P-QSLKKEFDLVCDRKNLKKTSQSVFMAGLLVGALVFGPVCDWIGRRPS--LLMQVLLSGITSMA 181

  Fly   223 TSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISL-----ELVGENYRSFVTVMTCTFYTSGIMLLS 282
            |:....|..:...|.::     |.....|::|.     |.||.::|:...|:..:....|.|:|:
Mouse   182 TAFVSSFELYLALRFVL-----ATANAGFLLSTNVLISEWVGPSWRTQAVVLAQSNVALGQMVLA 241

  Fly   283 GVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREF-PEA 346
            |:.|..|:|..|....:.|....|.|.:|:||||||||.:||.|||.:::::.|.||||.. ||.
Mouse   242 GLAYGVRNWRLLQITGTAPVLLLFFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLSPEL 306

  Fly   347 VHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGT 411
            :          ::|..:|...:...| ||.|.|::|..|:::...||.:..||..||:.....|.
Mouse   307 L----------NQLVPEKTGPSGNAL-DLFRHPHLRKVTLILIAVWFVDSLVYYSLSFQVGDFGL 360

  Fly   412 NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVS 476
            :.||:..:...||:|........|:..||:|....::.|.|:..:|.:.:|.|......||.:|.
Mouse   361 DIYVTQLIFGAVEMPGRFLSVLMMEKLGRKWSQLCTLTLAGIMYIIIIFIPGDLPTVVTVLAVVG 425

  Fly   477 KALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSM 541
            |...:|:|.|.|.:..||:||.:|..|:|..|....:|.|..|.:..|.:.:..:|:||.|.|.:
Mouse   426 KFASAAAFTISYVYTAELFPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHQAIPMVIFGSLPI 490

  Fly   542 LGGMTGLRLPETLHHRLPQTIEEGEE 567
            ..|:....||||....|..|:::.|:
Mouse   491 GAGLLCALLPETRGQTLKDTLQDLEQ 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	123/406 (30%)
		xylE	<306..>342	CDD:182225	20/35 (57%)
Slc22a13	NP_598741.2	2A0119	12..510	CDD:273328	153/533 (29%)