Protein Alignment CarT and sv2b

DIOPT Version :9

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_002933355.1
• Gene: sv2b / 100497731
• XenbaseID: XB-GENE-6041859
• Length: 711
• Species: Xenopus tropicalis
• Alignment Length: 766
• Identity: 146/766 - (19%)
• Similarity: 218/766 - (28%)
• Gaps: 314/766 - (40%)

  Fly     5 EDNDGDEY----DELSELRQRHKPESQPSVDEAFDLDDLLPTIGEFGKYQKLLVFGICLPACIPC 65
            :||....|    |..|........::|....|..|.||   .|.| |:||     ||
 Frog    37 QDNTYGGYSPNDDYYSGDHANQDEDAQSDATEGHDEDD---EIYE-GEYQ-----GI-------- 84

  Fly    66 GFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSLSIPKEL------------DNDELVY----- 113
                       ..|||            |.|.|:.||..|.            |.::|.|
 Frog    85 -----------PHPDD------------LRQHKASSIRDEFKDPADIIAERIEDEEQLAYQYENI 126

  Fly   114 -SKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDF-------DL 170
             .:|......||..:..|               |.....|.|.        .|:.|       |:
 Frog   127 IQECGHGRFQWTLFVVLG---------------LALMADGVEV--------FVVGFVLPSAEKDM 168

  Fly   171 VCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGS 235
            ...:.....:|| .:..|..:|.:::|.|.|:.||:....:.|....|.|.::|..:.:..:...
 Frog   169 CLSRSNKGMLGL-IVYLGMMLGAFVWGGLADKVGRKKCLIISLTINAAFSFVSSFVQGYGLFLFC 232

  Fly   236 RVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLS----------------GV 284
            |:|.|..|.....|.|....|.:....|.......|.|:..|.:..:                |.
 Frog   233 RLISGFGIGGSLPIVFAYFSEFLAREKRGEHLSWLCMFWMIGAVYAAAMAWSIIPHYGWGFSMGT 297

  Fly   285 TYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGRE--FPEAV 347
            .|....|.....|..||..|..:.:..||||||:||..|:.:||..||:.:...|.|.  .||.|
 Frog   298 HYHFHSWRVFVVICVLPCIASIIALKFMPESPRFLLETGKHDEAWMILKNIHDTNMRAKGEPEKV 362

  Fly   348 ----HLKLEAQ-------------------IR-RDKLKKQKKKMANVGLADLCRTPNMRLKTILI 388
                |:|...|                   :| ...:|:..:.|.:      |.:...|..||.:
 Frog   363 FTVSHIKTPKQPDEFIEIQSSTGTWFQRWFVRIMTVIKQIWENMLH------CFSGQFRKNTIFL 421

  Fly   389 TLSWFANETVYLGLSYYGPALG----------------------------------TNQ------ 413
            .:.||.     :.|||||..:.                                  .||
 Frog   422 AVVWFT-----MSLSYYGLTVWFPDTIRYLQDEDYASKVKRFTDENVKNFNFNFTLENQIHEDGE 481

  Fly   414 ------------YVSF------------------------------------------------- 417
                        ||:|
 Frog   482 YYNDRFYKMKLKYVTFKDSLFDECYFEDVTSTGSIFENCTIQNTVFYNTDLYQHKFIDCNFINVT 546

  Fly   418 ------------------------FLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVI- 457
                                    ||.::..||..:.....||..||...::.||::..|.|..
 Frog   547 FSQPKEGCHIDFEEDNDFLIYLVSFLGSLSVLPGNIISALLMDKIGRIRMIAGSMLISAVCCFFL 611

  Fly   458 ------------------TVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRGIGI 504
                              |.:...:|:|...|                     |||||..|....
 Frog   612 FFGNSESAMIGWQCLFCGTSIAAWNALDVVTV---------------------ELYPTNKRATAF 655

  Fly   505 GASSYIGGLGLI--GIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPET 553
            |..:.:..|..|  ...|.:::|...: :|:::.....:.||:..||||||
 Frog   656 GILNGLCKLAAIFGNSIFASFVGITKV-IPILLASTALVGGGLISLRLPET 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	135/723 (19%)
		MFS	182..551	CDD:119392	102/556 (18%)
sv2b	XP_002933355.1	synapt_SV2	1..711	CDD:130366	146/766 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910