Protein Alignment CarT and slc22a23

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_002936473.1
• Gene: slc22a23 / 100491610
• XenbaseID: XB-GENE-966989
• Length: 643
• Species: Xenopus tropicalis
• Alignment Length: 639
• Identity: 157/639 - (24%)
• Similarity: 241/639 - (37%)
• Gaps: 127/639 - (19%)

  Fly    35 DLD-DLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPE---------- 88
            |.| .:||.:|..|.|.|.||....:||.. ..|..|:..|:.|.||. ||::..
 Frog    57 DYDGSVLPFLGGLGSYNKRLVLLTWIPALF-LSFSQFSDFFLLDQPDK-WCQVNSSGGEHGPGRV 119

  Fly    89 -----------LLDLPLEQRKSLSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNA 142
                       ||.||..|..:...|              |...|:|       :..|.|.
 Frog   120 VSHVGNDSSGGLLLLPPPQLPTTPTP--------------TSATNYT-------DSCLCTK---- 159

  Fly   143 SWPLIKCPQGWEYNTSV-VWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRR 206
                      |:|.... :..::|..:|||||......|...:|..|...|..:.|.:.|..|||
 Frog   160 ----------WDYRIRAGLVQNVVSKWDLVCDSSWKVHIAKFSLLVGMIFGYLITGCVADWIGRR 214

  Fly   207 LSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTC 271
            |...:.:...|...|..:||.|...::..|...|..:..:....:.:.:||....:|..:|::..
 Frog   215 LVLLISVIFNLIFGLTVALSVDVNMFSTLRFFEGFCLAGIILSLYALRIELCPPGHRFMITMVAS 279

  Fly   272 TFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLE----EALKIL 332
            ....:|..||.|:..|.|||..|..:...||.....|..:.|||.|||:...:.:    :.||::
 Frog   280 FIGMAGQFLLPGIAALCRDWQVLQAVIICPFILMLFYWVIFPESLRWLMATMQFDASKKQILKMI 344

  Fly   333 ERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANET 397
            .| .:||.....:.|..:||    |:...:.||    |.:..:..|.|: .|.||:..   .|..
 Frog   345 HR-NRVNMESDVKGVMPELE----REVYTRPKK----VCIVKVVGTRNL-WKNILVLC---VNSL 396

  Fly   398 VYLGL------SYYGPALGT----NQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGG 452
            ...|:      |...|.|.|    |.||::|..|.:.|.|.|.....:...|||..|.|.|||..
 Frog   397 TGYGIHHCFAKSLMDPELNTSFMHNFYVNYFAMAGITLASCLAMCPVVGFLGRRGGLLLFMILTA 461

  Fly   453 VACVITVMLPDDAVDETLVLYLVSK----------ALLSASFLIIYP----------------FA 491
            :|.::.:.|          |.|:.|          .::...|.||:.                |.
 Frog   462 LASLLQLGL----------LNLIGKYSQRPETGLSDIVKNKFSIIFSIIGMFSSHAVGSLSVFFC 516

  Fly   492 GELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHH 556
            .|:.||.:||.|:|......|.|.:..|.:....:....|..:|....:::..:..|.|||:.:.
 Frog   517 AEITPTVIRGGGLGLVLASAGFGSLTAPIMELHNQKGYFLHHIIFACCTLICIICILLLPESKNQ 581

  Fly   557 RLPQTIEEGEEFGKNWQFKDCCRCAQKPEIL--SQPASYENLDVLAGSSTNASE 608
            .||:.|.|||.:.:......  |..::|.:|  |:...|..|......|...||
 Frog   582 NLPENIPEGEHYTRQPLLSH--RKGEQPLLLTNSELKDYSGLHDSVAMSDGISE 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	108/439 (25%)
		xylE	<306..>342	CDD:182225	12/39 (31%)
slc22a23	XP_002936473.1	MFS_SLC22A23	149..562	CDD:341002	111/456 (24%)