DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CarT and LOC100490946

DIOPT Version :9

Sequence 1:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_031756488.1	Gene:	LOC100490946 / 100490946	-ID:	-	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	548	Identity:	157/548 - (28%)
Similarity:	259/548 - (47%)	Gaps:	58/548 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKS 99
            |.|.|      |..:|.::|..:..|.|. .|...|..:|.|..| .|.||....:|.|
Frog     9 DKDSL------FSPFQAIMVTLLSAPLCF-VGTHNFMPVFAAAVP-PYNCRSNMTMDQP------ 59

  Fly   100 LSIPKELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSI 164
             ..|::         .|       ||.:.|         ..|::.|   |.:||||:.|:..|:|
Frog    60 -RYPED---------PC-------TQYVSS---------LSNSTKP---CEEGWEYDHSIFTSTI 95

  Fly   165 VIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAG-SLMTSLSKD 228
            :.::|||||:.....:..:....|..||..::|.|.||.||| :..:|....:|| .:..:||.:
Frog    96 ISEWDLVCDRQTLKEVAQSVYMAGVLVGAAVYGALADRFGRR-AMILCSLLQIAGMGIGVALSPN 159

  Fly   229 FWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGVTYLERDWVR 293
            ...:...|.:.|:.|..:......:::|.....||..|:::.....|.|.::|.|:.|..|.|..
Frog   160 IIVYCLFRFLTGMGICGLIINDLGLAMEWTPRRYRPIVSMIQGYGLTCGAIILVGLAYAIRGWRW 224

  Fly   294 LSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRD 358
            |....|||::.:||.|..:|||.|||.::....:||..|.|:||:|||:  |...:.|| .::.|
Frog   225 LQLTASLPYFIFFLLMCWVPESARWLSLKKHSNQALANLNRVAKINGRK--EGGPITLE-MLKLD 286

  Fly   359 KLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVV 423
            .....|.....:...||.|||.||..|::::||||::...:..::......|.:.|::..:.|..
Frog   287 DQHSTKAMTTKLTPLDLFRTPTMRTITLILSLSWFSSSFGFFAIALDVDRFGLSLYLTQGVFAGS 351

  Fly   424 ELP----SYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASF 484
            |||    :.:..:|.    |||..:|..:|..|...:.|:.:|.|.:...::|.:::||.|.:..
Frog   352 ELPIRILATITAFYI----GRRLTISFLLIFAGTLLLCTMAVPKDMLLLQMILTVLAKASLGSCI 412

  Fly   485 LIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLR 549
            :..|.:..|:|||.:|..|:|.::.:..||.|..|.:.........||:||...:.::.|:..|.
Frog   413 VCSYLYTAEVYPTVLRQTGLGFTNMMMRLGAIISPLVMITRVYVSFLPMVIFAVMPIISGLPILL 477

  Fly   550 LPETLHHRLPQTIEEGEEFGK--NWQFK 575
            |||||:..|..|:||.|...:  |:|.|
Frog   478 LPETLNCPLMDTVEEVESRNRELNFQIK 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	2A0119	44..561	CDD:273328	147/521 (28%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	106/373 (28%)
LOC100490946	XP_031756488.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.000