Protein Alignment CarT and slc22a2

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_002933908.1
• Gene: slc22a2 / 100487774
• XenbaseID: XB-GENE-965056
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 547
• Identity: 166/547 - (30%)
• Similarity: 268/547 - (48%)
• Gaps: 39/547 - (7%)

  Fly    37 DDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAFNQL-----FMADTPDDYWC---RIPELLDLP 93
            |:||..||||..:||.:...:|..:.:      |:.:     |:...| ||.|   .|||..: .
 Frog     5 DELLEHIGEFDAFQKQIFILLCFISVV------FSPIYVGIVFLGFVP-DYRCVSAGIPEPSN-E 61

  Fly    94 LEQRKSLSIPKELDNDELVYSKCYTYGVNW--TQLLESGEEDDLTTMEPNASWPLIKCPQGWEYN 156
            .|...:.:.|.. ..|.|..|:||.|.|:|  |.|..:....::|     :..|:..|..||:||
 Frog    62 CEWTLNYTGPNG-STDSLYMSQCYQYDVDWNSTSLNCTNSSLNIT-----SKLPITNCKDGWDYN 120

  Fly   157 TSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAG-- 219
            |:  .||:|.:|:|||..........:.:|.|..:|..:.|.:.||.||:  .|:..:.|:.|
 Frog   121 TT--GSSLVTEFNLVCGDSWKLDFFQSCVNIGFFIGGLISGYIADRFGRK--PFLISSILITGIF 181

  Fly   220 SLMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLSGV 284
            .::.:.:.::......|.|.|......:...:|:..|.||..:|..|.::....:|.|::|||||
 Frog   182 GILMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGV 246

  Fly   285 TYLERDWVRLSYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHL 349
            .|:...|..|....::|::.:..|.:.:|||||||:.:.|..||..|:..:||.||:..|:.:.
 Frog   247 AYVLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDFLE- 310

  Fly   350 KLEAQIRRDKLKKQKKKMANVGLADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQY 414
                .:..|:...:|:..:   ..||.|||.:|..|:::...||....||.|...:..:...|.|
 Frog   311 ----SLTADEEAGEKQVPS---FLDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIY 368

  Fly   415 VSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKAL 479
            ..||:||:||.||.:.....:|..|||:|..:..|:.|:.|:||..:|.......:.|..||:..
 Frog   369 FDFFISALVEFPSAILIIVTVDRVGRRYPWLVCCIITGITCLITAFIPHGYSWLIITLSCVSRMG 433

  Fly   480 LSASFLIIYPFAGELYPTQVRGIGIGASSYIGGLGLIGIPFITY-LGKDNLKLPLVIMGFLSMLG 543
            ::.|:.::.....|||||.:|.:||...|.:..||.:..|||.| |.....:|||::...|:.:.
 Frog   434 ITVSYEMVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYRLAAIWQELPLIVFAVLATVS 498

  Fly   544 GMTGLRLPETLHHRLPQTIEEGEEFGK 570
            |:....||||....||:||||.|...|
 Frog   499 GILVYFLPETKGRALPETIEEAENLHK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	120/401 (30%)
		xylE	<306..>342	CDD:182225	16/35 (46%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	156/529 (29%)