Protein Alignment CarT and sv2a

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_012825002.1
• Gene: sv2a / 100379721
• XenbaseID: XB-GENE-968429
• Length: 729
• Species: Xenopus tropicalis
• Alignment Length: 736
• Identity: 137/736 - (18%)
• Similarity: 228/736 - (30%)
• Gaps: 249/736 - (33%)

  Fly     5 EDNDGDEY---------DELSELRQRHKPESQPSVD--EAFDLDDLLPTIGEFGKYQKLLVFGIC 58
            |::|.|:|         |.|::       |...|.|  |..|.||   .|.| |:||     ||.
 Frog    50 EEDDDDDYQPQDGYYRGDPLND-------EEGASSDATEGHDEDD---EIYE-GEYQ-----GIP 98

  Fly    59 LPACIPCGFCAFNQLFMADTPDDYWCRIPELLDLPLEQRKSLSIPKELDND-ELVYSKCYTYGVN 122
            ....:.....|.||..:.:..|        ..||..:::|.   .:||... |::..:|......
 Frog    99 RADSMKGDHLANNQQLVTEFKD--------FNDLEGQRKKD---KEELAQQYEVILQECGHGRFQ 152

  Fly   123 WTQLLESGEEDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDF-------DLVCDQDIYPTI 180
            ||.....|               |.....|.|.        .|:.|       |:.........:
 Frog   153 WTLYFVLG---------------LALMADGVEI--------FVVGFVLPSAEKDMCLSDSNKGML 194

  Fly   181 GLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLTIPA 245
            || .:..|..||.:|:|.:.||.|||....:.|:.....:..:|..:.:.|:...|::.|:.|..
 Frog   195 GL-IVYLGMMVGAFLWGGMADRIGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGG 258

  Fly   246 VYQIPFIISLELVGENYRSFVTVMTCTFYTSGIMLLS----------------GVTYLERDWVRL 294
            ...|.|....|.:.:..|.......|.|:..|.:..|                |..|....|...
 Frog   259 SIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFQMGSAYQFHSWRVF 323

  Fly   295 SYITSLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGRE--FPEAVHLKLEAQIRR 357
            ..:.:.|.......:..||||||:.|..|:.:||..:|:::...|.|.  .||.|.     .:.:
 Frog   324 VLVCAFPSVFAIGALTTMPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVF-----SVTQ 383

  Fly   358 DKLKKQKKKMAN-------------VGLADL----------CRTPNMRLKTILITLSWFANETVY 399
            .|..||..::..             :.|.:|          |..|..|..|:::...||.....|
 Frog   384 IKTIKQDDELVEIQSDTGALHRRWMIKLLNLSQEVWANFHQCFAPEYRRITLMMMAVWFTMSFSY 448

  Fly   400 LGLSYYGP--------------------------------------------------------- 407
            .||:.:.|
 Frog   449 YGLTVWFPDMIKHLQNIDYASRTKYFHNESVNNFNFNFTLENQVHRKGEYHNDKFIGLKLKSVIF 513

  Fly   408 --ALGT----------------------------------------------------------- 411
              :|.|
 Frog   514 EDSLFTDCYFEDITSSNTFFKNCSFIRTMFYNTDLFDYKFINSKFTNSTFLHSKEGCQLDFSDDI 578

  Fly   412 -NQYVSFFLS---AVVELPSYLCCWYFMDTWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVL 472
             |.|:.:|:|   .:..||..:.....||..||...|:.|.::..::|..  :...::....:.|
 Frog   579 NNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCISCFF--LFFGNSESAMIAL 641

  Fly   473 YLVSKALLSASFLIIYPFAGELYPTQVRGIGIGASSYIGGL----GLIGIP-FITYLGKDNLKLP 532
            ..:...:..||:..:.....||||:..|....|   ::..|    .::||. |.:::|... .:|
 Frog   642 LCLFGGVSIASWNALDVLTVELYPSDKRTTAFG---FLNALCKLAAVLGISIFTSFVGVAK-AVP 702

  Fly   533 LVIMGFLSMLGGMTGLRLPET 553
            :::......:|....|:||||
 Frog   703 ILLASAALAVGSFLALKLPET 723

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	98/573 (17%)
		xylE	<306..>342	CDD:182225	12/35 (34%)
sv2a	XP_012825002.1	synapt_SV2	1..729	CDD:130366	137/736 (19%)