Protein Alignment CarT and slc22a5

DIOPT Version :10

• Sequence 1: NP_610052.1
• Gene: CarT / 35334
• FlyBaseID: FBgn0032879
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_021324939.1
• Gene: slc22a5 / 100000685
• ZFINID: ZDB-GENE-091012-1
• Length: 549
• Species: Danio rerio
• Alignment Length: 518
• Identity: 156/518 - (30%)
• Similarity: 247/518 - (47%)
• Gaps: 39/518 - (7%)

  Fly    67 FCAFNQL------------FMADTPDDYWCRIPELLDLPL-EQRKSLSIPKE-LDNDELVYSKCY 117
            ||..|.:            |:|.:| .:.||:    |:.| |.....|.|.| |.|.:|..|:|:
Zfish    22 FCLLNLIYISTGLHGLYIVFVAASP-AHRCRV----DVNLTEDWLEASAPTETLSNGDLQVSQCW 81

  Fly   118 TYGVNWTQLLESGE-----EDDLTTMEPNASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIY 177
            .|.:.....| ||:     :.::|.:      |..:|..||.|:..|..|:||.::|||||.:..
Zfish    82 RYSLQTLTNL-SGQGYSPGQINITDI------PRERCEDGWVYSADVYHSTIVSEWDLVCDSEWR 139

  Fly   178 PTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGSLMTSLSKDFWTWAGSRVIVGLT 242
            ..:..:.|..|..:|..:.|.|:||.||:...|..||.........|.|..:..:......:|..
Zfish   140 VPLASSTLYMGYLLGSIVSGQLSDRFGRKKVLFGSLAAEALLMFAQSFSPSWLIFCVLYFFIGAF 204

  Fly   243 IPAVYQIPFIISLELVGENYR-SFVTVMTCTFYTSGIMLLSGVTYLERDWVRLSYITSLPFYAYF 306
            ..::|...|::..|::..:.| .|.|:.....|..|.|||..|.:..|.|..|..:.|.....|.
Zfish   205 QISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYCVGYMLLPWVAFAIRHWRTLLRVLSGLTVVYI 269

  Fly   307 LYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPEAVHLKLEAQIRRDKLKKQKKKMANVG 371
            ...:::||||||||.:|.::|:..||...|:.|....||.:.  .::||:....:|.|     ..
Zfish   270 PLWWLIPESPRWLLSQGHVQESEAILRDAARKNRVPAPEVIF--KQSQIKEAAFQKSK-----YS 327

  Fly   372 LADLCRTPNMRLKTILITLSWFANETVYLGLSYYGPALGTNQYVSFFLSAVVELPSYLCCWYFMD 436
            ..|:.||.|:|..|.:..|.|.|....|.|||.....|..:.:::.|||||.|:|:|:...:.:.
Zfish   328 ALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVPAYIVSTFLLK 392

  Fly   437 TWGRRWPLSLSMILGGVACVITVMLPDDAVDETLVLYLVSKALLSASFLIIYPFAGELYPTQVRG 501
            :..||..||..:::||...::..::||......|.|.:..|...:.||.::|.:..|||||.:|.
Zfish   393 SCPRRPVLSAFLVIGGGFLLLVQLIPDRLQTLALALEMAGKFGFTMSFTVVYIYTAELYPTVLRN 457

  Fly   502 IGIGASSYIGGLGLIGIPFITYLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEE 564
            :|:|..|....:|.|..|:|.:||..|..||.|:||.|::...:..|.||||....||:.:|:
Zfish   458 LGMGMCSSAARIGSITAPYIIFLGTFNRHLPYVLMGSLTITASLANLFLPETFGKVLPENLEQ 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CarT	NP_610052.1	MFS_SLC22	152..551	CDD:340875	123/399 (31%)
		xylE	<306..>342	CDD:182225	14/35 (40%)
slc22a5	XP_021324939.1	MFS_SLC22A4_5_OCTN1_2	104..507	CDD:340934	126/415 (30%)