Protein Alignment Hr38 and nr4a1

DIOPT Version :9

• Sequence 1: NP_477119.1
• Gene: Hr38 / 35332
• FlyBaseID: FBgn0014859
• Length: 1078
• Species: Drosophila melanogaster
• Sequence 2: XP_012812696.1
• Gene: nr4a1 / 779756
• XenbaseID: XB-GENE-483315
• Length: 584
• Species: Xenopus tropicalis
• Alignment Length: 651
• Identity: 284/651 - (43%)
• Similarity: 365/651 - (56%)
• Gaps: 110/651 - (16%)

  Fly   460 QQQHLQLQLISPIGGPLSCGSSLPSFQETYSLKYNSSSGSSPQQASSSSTAAPTPTDQVLTLKMD 524
            |.||..|   |...||  |.:.:|..       .||..|.......:|..||.|......|. ||
 Frog    12 QAQHGSL---SQCAGP--CDNYVPDI-------LNSEFGKFTMDLVNSEIAASTSLPSFSTF-MD 63

  Fly   525 EDCFPPLSGGWSA---SPPAPSQLQQLHTLQSQAQMSHPNSSNNSSNNAGNSHNNSGGYNYHGHF 586
                 ..:|.:.|   ..|:.:|...|...:.|....:|.|..|..:..    .:|.|.:|:|..
 Frog    64 -----GYTGEFDAFLYQIPSSNQQSSLKVEEFQVFGCYPGSFTNQLDET----MSSSGSDYYGSP 119

  Fly   587 NAINASANLSPSSSASSLY---------EYNGVSAADNFYGQQQ--QQQQQSYQQHNYNSHNGER 640
            .:|       ||.|.....         .|...|...|:...:.  :||:.|..|..:.|.....
 Frog   120 CSI-------PSPSTPGFQNPQLPTWECSYGAYSPTQNYDNMRHWTEQQKSSISQQTFFSFGTPA 177

  Fly   641 YSLPTFPTISELAAAT-----AAVEAAAAATVSSPSVGGP-------PPVRRASLPVQRTVSPAG 693
            :|........::|.||     ..|:|...|...:.|.|.|       |.|...|:.:...:||
 Frog   178 HSPNMAANPMKIAPATHRLDQQVVDADVFALAQNSSAGFPAIPLGQAPGVLDNSVLLDSPLSP-- 240

  Fly   694 STAQSPKLAKITLNQRHSHAHAHALQLNSAPNSAASSPASADLQAGRLLQAPSQLCAVCGDTAAC 758
                                            |...||:|.:   ||        ||||||.|:|
 Frog   241 --------------------------------SKTRSPSSNE---GR--------CAVCGDNASC 262

  Fly   759 QHYGVRTCEGCKGFFKRTVQKGSKYVCLADKNCPVDKRRRNRCQFCRFQKCLVVGMVKEVVRTDS 823
            |||||||||||||||||||||.:||:|||:|:||||||||||||||||||||.||||||||||||
 Frog   263 QHYGVRTCEGCKGFFKRTVQKNAKYICLANKDCPVDKRRRNRCQFCRFQKCLAVGMVKEVVRTDS 327

  Fly   824 LKGRRGRLPSKPKSPQESPPSPPISLITALVRSHVDTTPDPSCLDYSHYEE------QSMSEADK 882
            |||||||||||||...|   |.|:|||.:|||:|:|:.|..|.||||.::|      :..|.||
 Frog   328 LKGRRGRLPSKPKQIAE---SSPVSLINSLVRAHIDSIPSSSKLDYSKFQENVPVQLEKESSAD- 388

  Fly   883 VQQFYQLLTSSVDVIKQFAEKIPGYFDLLPEDQELLFQSASLELFVLRLAYRARIDDTKLIFCNG 947
            |||||.||:.|::||:::||||.|:.:|..|||:||.:||.||||:||||||:|.::.|||||||
 Frog   389 VQQFYDLLSGSLEVIRKWAEKIQGFVELPKEDQDLLLESAFLELFILRLAYRSRPEEGKLIFCNG 453

  Fly   948 TVLHRTQCLRSFGEWLNDIMEFSRSLHNLEIDISAFACLCALTLITERHGLREPKKVEQLQMKII 1012
            .|||||||:|.||||::.|:|||.:|....||:.:|:||.||.:||:||||:||||||:||.:||
 Frog   454 VVLHRTQCVRGFGEWIDSIIEFSHNLQRTNIDVPSFSCLSALVIITDRHGLKEPKKVEELQSRII 518

  Fly  1013 GSLRDHVTYNAEAQKKQHYFSRLLGKLPELRSLSVQGLQRIFYLKLEDLVPAPALIENMFVTTLP 1077
            ..|::||..:...|.:.:..|:|||||||||:|..||||||||||||||||.|.:::.:|:.|||
 Frog   519 NCLKEHVPSSMNEQNRPNCLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPPIVDKIFMDTLP 583

  Fly  1078 F 1078
            |
 Frog   584 F 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr38	NP_477119.1	NR_DBD_NGFI-B	747..821	CDD:143527	63/73 (86%)
		NR_LBD_DHR38_like	849..1078	CDD:132757	133/234 (57%)
nr4a1	XP_012812696.1	NR_DBD_NGFI-B	251..325	CDD:143527	65/81 (80%)
		NR_LBD_NGFI-B	347..584	CDD:132762	135/237 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	234	1.000	Domainoid score	I2326
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D216479at33208
OrthoFinder	1	1.000	-	-		FOG0001568
OrthoInspector	1	1.000	-	-		otm48869
Panther	1	1.100	-	-	O	PTHR24085
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3016
SonicParanoid	1	1.000	-	-		X978
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.050