Protein Alignment Cen and centrocortin

DIOPT Version :10

• Sequence 1: NP_610049.1
• Gene: Cen / 35330
• FlyBaseID: FBgn0032876
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: XP_061511823.1
• Gene: centrocortin / 1271993
• VectorBaseID: AGAMI1_010849
• Length: 902
• Species: Anopheles gambiae
• Alignment Length: 924
• Identity: 312/924 - (33%)
• Similarity: 433/924 - (46%)
• Gaps: 221/924 - (23%)

  Fly    21 DLQLAAELGKTLLERNKELETFIKEYK--IKGDEQELEILHLRKHINAMTEVNDSRLKVYEQLEV 83
            ||||||||||||||||||||..:|.::  |:...||:|  :|.|...|:.||||||:|:||||||
Mosquito    26 DLQLAAELGKTLLERNKELEATLKHHQNIIEDHVQEIE--YLTKQNAALREVNDSRMKIYEQLEV 88

  Fly    84 GIQDLERANQRLNLEKNRDKKQIKTLTTNTEVLEARCEELSQLLSDARQSLSTERR--KVD---- 142
            .||||||...:|.||...:||.:|.|.:|.|.||.:.|||::.|.|||:.:..:||  |.:
Mosquito    89 SIQDLERDKYKLALEYQAEKKHVKQLCSNIESLETKVEELTRSLEDARRQVEADRRTKKTERLLG 153

  Fly   143 -QYQQERYRMQ-----HSTEGSVSSHSIQSLCKEQSVEFSK-------------------LDVMA 182
             |.||::...|     :|.....|..:|.::..::.|..|:                   .|..|
Mosquito   154 QQQQQQQLPGQPAIVINSPTSHASKDAIPNVPSQEGVSTSRQTTEPCQSAKPMPAGAARQSDPAA 218

  Fly   183 IANSTGLEDISFSNATMCER----TA---VKGEDNEELVKLLSEMEVLKRDFLAEQQRCTELEEQ 240
            .:...|...........|||    ||   ...||:||:::::.|:|..::..|:||.:..:||||
Mosquito   219 PSAGAGEPRTEEDGTEQCERDGGPTADDHTLSEDSEEMLRIMQELERTQKCLLSEQGKVGDLEEQ 283

  Fly   241 LVTIIQDNQGLQTRLLENSANEGTMSMHEEFSLLDDVRQGQMCSRCLRDINESNTNMDDQSSIAP 305
            |..|.|:|..||::||...:.| ..|:|:|.|:|::.|||.:|:|||||:.|   ..|:.|.|..
Mosquito   284 LAVIAQENTALQSKLLNVHSTE-IRSVHDELSMLEEFRQGPVCTRCLRDLGE---QQDEDSIITG 344

  Fly   306 TEEIYEDDDRSILSESTSKCDNSGADYKERFRIP-----EDLNPNSSD--------KPNPYRDLV 357
            |.|    ||.|::....:      .|:.:.:|..     |...|:|.|        ..||||:||
Mosquito   345 TTE----DDASLMELIRN------TDFPQAYRSSVTIEIEPTKPDSLDLALSECAGPTNPYRELV 399

  Fly   358 EKYEALVEVKRTSNAVKSNFTSNPDGKTMTESS-QGKKSETIVNSSKESDLMLDST--------- 412
            ||||||:||.|.....|| .|:.|.|.....:. .|..:.|.|:|.:...|:.|:.
Mosquito   400 EKYEALLEVHRQPLGQKS-ATAAPTGAPGPATGVAGSGNNTPVDSCQPQQLLADAADLLPCGPST 463

  Fly   413 --------RKRTPTEFSE---------SETTSSGFSDETSNKSTQTDERPSYFLCSISNGNDCKF 460
                    .:..|.|..:         |||.|||:|||.|||:|||||.|..|||:|::|.|.:|
Mosquito   464 LGAGGDAPERAGPGERRDGRAVAATECSETASSGYSDEVSNKATQTDESPRNFLCTIADGKDWRF 528

  Fly   461 SIYDDVSPIESHFRNRPEYRELFKEIFGVLKKAADNNEE-DKLPSLHDDAQITEKLPLVAAK--- 521
            :||:|.|.|:|.||..|.:||||:|||.||:|||:|.:| |:||.|.|........|..||:
Mosquito   529 NIYEDDSAIDSRFRFSPAHRELFREIFSVLRKAAENRDEGDQLPLLDDTKPGAANPPPAAARPGG 593

  Fly   522 ------VPPVTPEREESP------------------DDFIDDTQSVV-SSVISNQSIAMSECVTK 561
                  ||||||..:|.|                  ||.:.:|.|.| ||.:|.||.|||||:||
Mosquito   594 GAAAVTVPPVTPANDEPPTGFGLEKDGQQGEGAVEQDDEVGETVSFVSSSAVSEQSFAMSECITK 658

  Fly   562 LERKTAKKHIFDVRNQQNQSSLTQSTLLNSSSKETTVGEPNYKPIRENGQILTPLKREPLEYLTV 626
            .||:..      .|..:.............::.....|:....|    |.|       ||||::|
Mosquito   659 SERRRI------ARQAKAAGRYADGEQQGPNNGADAAGQKPSGP----GYI-------PLEYISV 706

  Fly   627 GVGIK--KKNRRKHRNQSSSGDRIELFNSREFTPRNSPLAMNNRGGGQGSSKMCTDT-------- 681
            .||::  |..||.||...:            .||:.:...    |||..::...|.|
Mosquito   707 SVGVRKGKSRRRSHRRDEA------------HTPQGAAAG----GGGAAAAGAATTTPTPPRSGS 755

  Fly   682 ---------------------------LNAEFGRSNRRR-------TTPSSSNWNGSPMVIY--- 709
                                       .:|..||.:|..       ||.:::....|...::
Mosquito   756 ARKHRTSFRPWNPERDGGVAIAADAASWSASAGRGHRSATPLSNAGTTTTATATPPSAAAVHPGS 820

  Fly   710 -------NKNMNTPQTSRGRVIEL-------NGVEFYHNTVSQDLHKLKKLDLSYAEVLRRADAG 760
                   .|..|.....|.|..:|       ..|||..::.||.||||:||||||||||||||.|
Mosquito   821 SRTSRRSEKKRNATAGLRNRYADLMQDALGDEVVEFRPSSASQHLHKLQKLDLSYAEVLRRADGG 885

  Fly   761 EHGPT-RSHSQRQQ 773
            ...|. |.::|.||
Mosquito   886 HPFPARRQYNQPQQ 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cen	NP_610049.1	SMC_prok_B	<30..>270	CDD:274008	100/279 (36%)
centrocortin	XP_061511823.1	None