Protein Alignment Cen and Cdr2

DIOPT Version :9

• Sequence 1: NP_610049.1
• Gene: Cen / 35330
• FlyBaseID: FBgn0032876
• Length: 790
• Species: Drosophila melanogaster
• Sequence 2: NP_031698.2
• Gene: Cdr2 / 12585
• MGIID: 1100885
• Length: 455
• Species: Mus musculus
• Alignment Length: 530
• Identity: 127/530 - (23%)
• Similarity: 211/530 - (39%)
• Gaps: 150/530 - (28%)

  Fly    21 DLQLAAELGKTLLERNKELETFIKEYKIKGDEQELEILHLRKHINAMTEVNDSRLKVYEQLEVGI 85
            |||||||||||||:||.|||..:::......||..||.:|.|.:..:.::|:...||||||:|..
Mouse    26 DLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTA 90

  Fly    86 QDLERANQRLNLEKNRDKKQIKTLT-------TNTEVLEARCEEL-SQLLSDARQSLSTERRKVD 142
            ::||..||:|..|....:::|.:||       ||.:.|:::.||| |......||....:.:...
Mouse    91 RELEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQVEELKSSSQGRGRQKACDQEKPAP 155

  Fly   143 QYQ--QERYRM-QHSTEGSVSSHSIQSLCKEQSVEFSKLDVMAIANSTGLEDISFSNATMCERTA 204
            .:.  :|.|.: ||.....|.:..|.||..:||.:
Mouse   156 SFSCLKELYDLRQHFVYDHVFAEKITSLQSQQSPD------------------------------ 190

  Fly   205 VKGEDNEELVKLLSEMEVLKRDFLAEQQRCTELEEQLVTIIQDNQGLQTRLLENSANEGTMSMHE 269
              .|:||.|.|.::   :|:.....|:::...:|.:...::::|..|:.:|....|..
Mouse   191 --EEENEHLKKAVT---MLQAQLSLERKKRVSVEAEYKVVLKENSELEQQLGATDAYR------- 243

  Fly   270 EFSLLDDVRQGQMCSRCLRDINESNTNMDDQSSIAPTEEIYEDDDRSILSESTSKCDNSGADYKE 334
                          :|.|          :.::.:|...::.:.:...:          :|.
Mouse   244 --------------ARAL----------ELEAEVAEMRQMLQAEHPFV----------NGV---- 270

  Fly   335 RFRIPEDLNPNSSDKP--NPYRDLVEKYEALVEVKRTSNAVKSNFTSNPDG--KTMTESSQGKKS 395
                 |.|.|:|...|  .|.:.|:|:.                |.:.|:.  |.:..||    |
Mouse   271 -----EKLVPDSLFVPFKEPSQSLLEEM----------------FLAAPEAPRKPLKRSS----S 310

  Fly   396 ETIVNSSKESDLMLD----------STRKRTPTEFSESETTSSGF--------------SDETSN 436
            ||.::|....|::.|          :.::|..:...|.:|..|..              .|..|:
Mouse   311 ETALSSLAGDDIVKDHEDTCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQQEQDSLSH 375

  Fly   437 KSTQTDERPSYFLCSISNGNDCKFSIYD--DVSP--IESHFRNRPEYRELFKEIFGVLKKAADNN 497
            |:.||....:..|..:...::...|.::  .|||  |.|.....|||:.||||||..:||.....
Mouse   376 KAVQTSRLLTRDLTGLVTQSEAGASGWEPTPVSPESISSPTTTPPEYKALFKEIFSCIKKTKQEI 440

  Fly   498 EED--KLPSL 505
            :|.  |.|||
Mouse   441 DEQRTKYPSL 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cen	NP_610049.1	SMC_prok_B	<13..>255	CDD:274008	70/244 (29%)
Cdr2	NP_031698.2	SMC_prok_B	<19..>262	CDD:274008	75/301 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..152		6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	395..419		6/23 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849807
Domainoid	1	1.000	95	1.000	Domainoid score	I7405
eggNOG	1	0.900	-	-		E1_2C4BD
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	95	1.000	Inparanoid score	I5045
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003445
OrthoInspector	1	1.000	-	-		otm42372
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19232
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5462
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.970