Protein Alignment CG31678 and SLP1

DIOPT Version :9

• Sequence 1: NP_724277.2
• Gene: CG31678 / 35327
• FlyBaseID: FBgn0051678
• Length: 1417
• Species: Drosophila melanogaster
• Sequence 2: NP_014797.1
• Gene: SLP1 / 854325
• SGDID: S000005680
• Length: 587
• Species: Saccharomyces cerevisiae
• Alignment Length: 651
• Identity: 144/651 - (22%)
• Similarity: 243/651 - (37%)
• Gaps: 195/651 - (29%)

  Fly   148 STAQVPNNQLNYNKRSSAG--KVHRFSESQQLDQPKQLEQEEPATGQPKAPELQEPPQLPQAEES 210
            :|....|.|..::...|.|  :.|.|.::.::| .:|.:..|  .|:.|..:....|..|:
Yeast    42 TTGSTTNVQKEHSSPLSTGSLRTHDFRQASKVD-IRQADIRE--NGERKEQDALTQPATPR---- 99

  Fly   211 FPEIITELPAVTITELPLDRVMNRLDSVILDGSPATAGNH--SDEEQHQQQQQPHEDQPMQVSEA 273
                                            :|..:.|.  |.:|..:.:.:.|...|
Yeast   100 --------------------------------NPGDSSNSFLSFDEWKKVKSKEHSSGP------ 126

  Fly   274 DEEVPQKDEQMPKINDPGGGIQVEGMVTPEAATVGETQESSEELQPGSAAFNGTEGTANLTNANE 338
                   :..:.::.:|     |:.....|...:||..|..               ...|||.|
Yeast   127 -------ERHLSRVREP-----VDPSCYKEKECIGEELEID---------------LGFLTNKN- 163

  Fly   339 EVPMPVFSEWAQKQMEAEASREQAMELEQQVVNKSAQRKNNTGSSSGKPPTLKLRSKNYASPDCG 403
                    ||::::...:...      |::.:.|..::|                 .||||.||.
Yeast   164 --------EWSEREENQKGFN------EEKDIEKVYKKK-----------------FNYASLDCA 197

  Fly   404 AKIIAHNSESKHTEAVLTQSTDEYMLSTCES-RIWFVVELCEAIQAQKVDVANYELFSSSPKNFT 467
            |.|:..|.|:....:.|.:|.|:|:|:.|.: :.:.|:||||.|..:::::||||.|||:.|.|.
Yeast   198 ATIVKSNPEAIGATSTLIESKDKYLLNPCSAPQQFIVIELCEDILVEEIEIANYEFFSSTFKRFR 262

  Fly   468 VAVSKRFP--TRDWSNVGRFAAEDKRTIQTFELH-PHLFGKFVRVDITSHYANEHFCPLSLFRVF 529
            |:||.|.|  ..:|:.:|.|.|.:.|.:|.|::| |.::..:::::|.|||.:|.:||:||.:|:
Yeast   263 VSVSDRIPMVKNEWTILGEFEARNSRELQKFQIHNPQIWASYLKIEILSHYEDEFYCPISLIKVY 327

  Fly   530 GTSEYEAFETEIRPSDDLDDFYDDYGAQEQKAAVGSGGNIFQSASDAVMQMVKKAAEVLVKPTKA 594
            |.|..:.|:            .|...|||.|.. ..|.|...:.::..:|.
Yeast   328 GKSMMDEFK------------IDQLKAQEDKEQ-SIGTNNINNLNEQNIQD-------------- 365

  Fly   595 LKWSEESVLCQTPAFEAFSCINCNTTLVERINSLLSC-------QFQQLQALLSLSHLRSDLLNS 652
             :.:......:||          ||:.:..:...|||       :|.:...:|:.|...|..:.|
Yeast   366 -RCNNIETRLETP----------NTSNLSDLAGALSCTSKLIPLKFDEFFKVLNASFCPSKQMIS 419

  Fly   653 ---------------------RVCQEEFGISLTGSEFASKMGKEQSYFLS----MLPAEHVGAMC 692
                                 |:.|.|...|||.|..     :|||..||    .|...|.....
Yeast   420 SSSSSAVPVIPEESIFKNIMKRLSQLETNSSLTVSYI-----EEQSKLLSKSFEQLEMAHEAKFS 479

  Fly   693 KLIQAEQNVTDHNHTKAPSLKQHVSSPEPVQDNATATGVRQDCENSKTPTKEPLTPSLEVVVPEV 757
            .|      ||..|.|...:|....:....::|.:......|..||.|...:..|  .||.:..||
Yeast   480 HL------VTIFNETMMSNLDLLNNFANQLKDQSLRILEEQKLENDKFTNRHLL--HLERLEKEV 536

  Fly   758 S 758
            |
Yeast   537 S 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31678	NP_724277.2	Sad1_UNC	409..532	CDD:285038	48/126 (38%)
SLP1	NP_014797.1	Sad1_UNC	204..330	CDD:400199	48/125 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343281
Domainoid	1	1.000	103	1.000	Domainoid score	I1507
eggNOG	1	0.900	-	-		E1_KOG1396
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003583
OrthoInspector	1	1.000	-	-		oto99339
orthoMCL	1	0.900	-	-		OOG6_103990
Panther	1	1.100	-	-	LDO	PTHR12953
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1347
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.860