DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2614 and AT2G31740

DIOPT Version :9

Sequence 1:	NP_610045.1	Gene:	CG2614 / 35326	FlyBaseID:	FBgn0032873	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_850171.1	Gene:	AT2G31740 / 817731	AraportID:	AT2G31740	Length:	760	Species:	Arabidopsis thaliana

Alignment Length:	735	Identity:	205/735 - (27%)
Similarity:	332/735 - (45%)	Gaps:	155/735 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KTREEFAQTDYWNEFFKKRG-EKAFEWYGEYLELCDQIHKYIKPAD-------RILMLGCGNSKL 62
            :|.|:|...:.|::||..|| :.:||||.|:.:|.|.:...::.:.       :||:.|||||:|
plant    18 QTLEDFTSKENWDKFFTLRGNDDSFEWYAEWPQLHDSLLPLLQDSSSSSSDSLQILVPGCGNSRL 82

  Fly    63 SMDMYDTGFRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMTFPDESFSVSLDKGTLDAL 127
            :..:||.|||||||:|.|.:.:..||..|.::|||:::..||.|.|...||||...||||.||||
plant    83 TEHLYDAGFRDITNVDFSKVVISDMLRRNIRTRPELRWRVMDITKMQLADESFDTVLDKGALDAL 147

  Fly   128 FADDEPETRAVVEN-YFKEILRTMRNGGRYVGISLLQEHILNFLLD---FLPKHNCMLRIVHCLG 188
            .   |||....:.| |..|..|.::.||:::.::|.:.|:|..|..   |..|.|     ||.:.
plant   148 M---EPEVGTKLGNQYLSEAKRVLKPGGKFICLTLAESHVLALLFSRFRFGWKMN-----VHSIA 204

  Fly   189 VEQANKEKNADDALTLPVFVVVATKFKSLPMPVLEFGF-----GNDKMQRFTTVSELNSAVSSVQ 248
            .:::.          |..::|||.|..|:.:..:...|     |.:..|.    |.:..||.|..
plant   205 QKRSK----------LKTYMVVAEKENSVLLHEITSAFELVSLGRNDSQG----SGMREAVESEN 255

  Fly   249 KAALVCN---------------------------------GLARSNIAGHNEVIMDLHRPSEQTP 280
            |....||                                 |...||.: :..|::|..:.:|...
plant   256 KIRRDCNNGSDLLYSHEDLKLGIKGDLAELTEGRRIKFTLGGQGSNFS-YRAVLLDAQKQTEPFV 319

  Fly   281 RYTIHILDKPPARGLGKYAAFIVPQGREVEWIFSTPAGRKKLQDSANFQRLAVVTLHRDQVYSTL 345
            .|.               ..|:||:.|..||:|.:..|:.::.:|:...||.:|.|......:|:
plant   320 YYC---------------GVFLVPKTRAHEWLFCSEEGQWQVVESSQAARLIMVFLDSSHSGATM 369

  Fly   346 DEVKQELADSIKNLSPAGLTD-QIPYLSLGSDVGKRETLICGFSKISGDFRIEEV---------- 399
            ::::.:|:..:..|:|....: :|||:.....:.||:|:....|.::|...:|:|
plant   370 EDIQNDLSPMVTQLAPRNDDEARIPYMMASDGIKKRDTVHEVTSPMTGKVVVEDVVYESAPSNLE 434

  Fly   400 ---EANGKTLRRLIFLSNQFVVQSEAL------------------VKTVKIKGKKDRK------- 436
               .::....|||:|...:.::|||||                  |...|.||.|.:.
plant   435 DLSTSSDLAFRRLVFKRTEGLIQSEALLVEDGEILEQSQKEKTKNVSQSKRKGNKKQNQEPSRPL 499

  Fly   437 -KIDFGYLACQHHLYMSVGVQLATTVQHPKRDVEKDV--LVVGLGGGGLCSFLHAALPQARITAV 498
             ::...|||..:|..:..|..|.::...........|  :|:|||.|.|..|||..||...|.||
plant   500 MRVSHDYLASSYHTGIISGFTLVSSYLKKAESCGTMVKTVVIGLGAGLLPMFLHGCLPFFSIEAV 564

  Fly   499 EIDPIMLEVAEQYFELKQDKRFHVVIDDGLDFVERCRNED-----------------------IH 540
            |:||:||.|.:.||...|:.|..|.|.||:.|:....|.:                       |.
plant   565 ELDPVMLSVGKDYFGFTQNDRLKVHIADGIKFIRDITNSEASSEESSNIGSNGDSTTHNTQGGIC 629

  Fly   541 FDAVLFDVDSKDLSLGMSCPPQSFLATKILQHIKEIIGPKGLFMLNLVCRDESLRTEALNNLHKV 605
            .|.::.||||.|.|.|::||...|:....|..:|:.:...|||::|||.|.:|::...::.:.||
plant   630 PDILIIDVDSADSSGGLTCPASDFIEETFLLSVKQALPQHGLFIVNLVTRSQSVKDMVVSRMKKV 694

  Fly   606 FPAVCSYKLEE--DINEIIY 623
            |..:...:|||  |:|.:::
plant   695 FDHLFGLQLEEEDDVNVVLF 714

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2614	NP_610045.1	AdoMet_MTases	55..157	CDD:302624	48/102 (47%)
CG2614	NP_610045.1	AdoMet_MTases	<483..>612	CDD:302624	49/151 (32%)
AT2G31740	NP_850171.1	Methyltransf_11	76..176	CDD:400514	48/102 (47%)
AT2G31740	NP_850171.1	AdoMet_MTases	<539..716	CDD:418430	60/176 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I2441
eggNOG	1	0.900	-	-		E1_KOG2352
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32285
Inparanoid	1	1.050	260	1.000	Inparanoid score	I976
OMA	1	1.010	-	-		QHG57818
OrthoDB	1	1.010	-	-		D912165at2759
OrthoFinder	1	1.000	-	-		FOG0006581
OrthoInspector	1	1.000	-	-		oto3000
orthoMCL	1	0.900	-	-		OOG6_100611
Panther	1	1.100	-	-	O	PTHR12176
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5580
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840