Protein Alignment CG2614 and mettl13

DIOPT Version :10

• Sequence 1: NP_610045.1
• Gene: CG2614 / 35326
• FlyBaseID: FBgn0032873
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001038234.3
• Gene: mettl13 / 557908
• ZFINID: ZDB-GENE-060929-60
• Length: 690
• Species: Danio rerio
• Alignment Length: 704
• Identity: 287/704 - (40%)
• Similarity: 420/704 - (59%)
• Gaps: 46/704 - (6%)

  Fly     1 MNLLPKTREEFAQTDYWNEFFKKRGEKAFEWYGEYLELCDQIHKYIKPADRILMLGCGNSKLSMD 65
            |:|||:|.|||:..|||..||:|||||||||||:|..||..:||||||.|::|::|||||:||..
Zfish     1 MSLLPRTAEEFSSADYWERFFRKRGEKAFEWYGDYNSLCGVLHKYIKPRDKVLVVGCGNSELSEQ 65

  Fly    66 MYDTGFRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMTFPDESFSVSLDKGTLDALFAD 130
            :||.|:|.:||||||...|..|.:.||:.||::.|.|:|||...|...||.|:||||||||:.::
Zfish    66 LYDVGYRQLTNIDISETVVSHMNQRNAERRPDLSFQQLDATQTGFESGSFQVTLDKGTLDAMASE 130

  Fly   131 DEPETRAVVENYFKEILRTMRNGGRYVGISLLQEHILNFLLDFLPKHNCMLRIVHCLGVEQANKE 195
               |..|:......|:.|.:..|||||.|:|.|||::...::...| ...:| |||| ..|.|:|
Zfish   131 ---EDGALAGRMLAEVGRVLAVGGRYVCITLAQEHVIKLAVEHFVK-GWAVR-VHCL-TGQQNEE 189

  Fly   196 KNADDALTLPVFVVVATKFKSL-PMPVLEFGFGND-KMQRFTTVSELNSAVSSVQKAALVCNGLA 258
              :|.:..|||||:|.|||:.. |..|||...|.| ...|..:|.||.|||...|...|:.:.|
Zfish   190 --SDSSFALPVFVLVCTKFRQAPPFAVLELCQGEDGAPARLASVEELLSAVKERQAYNLMLHKL- 251

  Fly   259 RSNIAGHNEVIMDLHRPSEQTPRYTIHILDKPPARGLGK---YAAFIVPQGREVEWIFSTPAGRK 320
            |......:...:.|...:...||||:.|.|.||:....:   :|.||||||||.:|::.:..||.
Zfish   252 RGGTDSSSTPSLTLCHAASGRPRYTLTIQDGPPSAKTPRSNHFAIFIVPQGRESDWLYGSAEGRA 316

  Fly   321 KLQDSANFQRLAVVTLHRDQVYSTLDEVKQELADSIKNLSPAGL--TDQIPYLSLGSDVGKRETL 383
            :|..||.|:||.:|.:||||.|..:..|:.||:..:..|:|.|:  ..|:|:||:|.|:|.||.:
Zfish   317 QLASSAKFRRLVIVAMHRDQEYEDMQAVQSELSPVVMELAPPGMPANQQVPFLSVGGDLGWREVI 381

  Fly   384 ICGFSKISGDFRIEEVEA-NGKTLRRLIFLSNQFVVQSEALVKTV-------KIKGKKDRKK--- 437
            ..|.|.::|::.:|:|.. :|...|||||::|..:||||:.:::.       |.|.||..|:
Zfish   382 GRGLSALTGEYSVEDVRGEDGYLYRRLIFMNNSQLVQSESRLQSAAAASSASKKKNKKKAKQPAS 446

  Fly   438 -------IDFGYLACQHHLYMSVGVQLATTVQHPKRDVEKDVLVVGLGGGGLCSFLHAALPQARI 495
                   :|.|:|.|.||..|..|:.:........:|....||:||||||||..|:...:|.||:
Zfish   447 TGAKDRSVDRGFLCCTHHEVMVAGLAMLGMDAINNKDQPVSVLLVGLGGGGLPQFVRDFVPCARV 511

  Fly   496 TAVEIDPIMLEVAEQYFELKQDKRFHVVIDDGLDFVERCRNE-DIHFDAVLFDVDSKDLSLGMSC 559
            ..||:||::|:||:.:|..:.|.|..|.:.|||:.:....:| :.:||.::|||||||.:|||||
Zfish   512 EVVELDPVVLDVAQTWFGFQIDDRLKVTLGDGLEHITTLESEGERYFDVIMFDVDSKDTTLGMSC 576

  Fly   560 PPQSFLATKILQHIKEIIGPKGLFMLNLVCRDESLRTEALNNLHKVFPAVCSYKLEEDINEIIYC 624
            ||.:|:.|.:|:.:..::.|:|||||||||||.:||...|:.:|.|||.|.|..:|.::||::.|
Zfish   577 PPPAFVETSLLKKVYSLLSPRGLFMLNLVCRDSALRKSVLDRVHSVFPCVFSRGIEGEVNEVLLC 641

  Fly   625 ---ANDEKYKTVEQWKKNMGTAGRGLNSAVKETKLASEDA--LEVAEFLSELKI 673
               :.:.|..||.|      |..:......|..:..|:.|  :::...|::||:
Zfish   642 CRSSGEHKPHTVPQ------TLQQTAKDLQKTLRANSQTAPQIDITAMLNDLKV 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2614	NP_610045.1	Methyltransf_25	52..154	CDD:463945	45/101 (45%)
		SpeE	<478..612	CDD:440190	63/134 (47%)
mettl13	NP_001038234.3	UbiE	46..167	CDD:441828	59/123 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	427..451		5/23 (22%)
		SpeE	<494..626	CDD:440190	62/131 (47%)