DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2614 and F52F12.9

DIOPT Version :9

Sequence 1:	NP_610045.1	Gene:	CG2614 / 35326	FlyBaseID:	FBgn0032873	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001021486.2	Gene:	F52F12.9 / 3565818	WormBaseID:	WBGene00009942	Length:	351	Species:	Caenorhabditis elegans

Alignment Length:	363	Identity:	79/363 - (21%)
Similarity:	137/363 - (37%)	Gaps:	91/363 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   320 KKLQDSANFQRLAVVTLHRDQVYSTLDEVKQELADSIKNLSPAGLTDQIPYLSLGSDVGKR---- 380
            |:|.|...:.  ||:..|.:...:.:  :..|..|...|.:...:.|:|.|...|:....|
Worm    37 KELTDEEFYD--AVLMKHFENKNNKV--IAAECPDPKDNSTCLYIIDRIGYFKDGTWFVARFLTP 97

  Fly   381 -ETLICGFSKISGDFRIEEVEANGKTLRRLIFLSNQFVVQSEALVKTVKIKGKKDRKKIDFGYL- 443
             ..|:.||..||             .|.:.:|.:|:....:|              ..:|.||:
Worm    98 APHLMKGFLSIS-------------RLAKPVFKTNRTANTAE--------------WPVDVGYMD 135

  Fly   444 -----ACQHHLYMSVGVQLATTVQHP-KRDVEKDVLVVGLGGGGLCSFLHAALPQARITAVEIDP 502
                 |.:.....|.|       ..| ..|:.:||..:|:..|||.||:.......::|.|:|||
Worm   136 PLTPNAVEFTTLFSTG-------HFPLNHDITRDVTFLGVATGGLMSFMAEYFKNMKLTGVDIDP 193

  Fly   503 IMLEVAEQYFELKQDKRFHVVIDDGLDFVERCRNEDIHFDAVLFD-------VDSKDLSLGMSCP 560
            ....:|:::|..:..|...:.|.||.:|:::........||||.|       ||.      :.||
Worm   194 QSEYLAKKWFGYQNRKNDRIFIADGAEFIKQMAENGETSDAVLVDACHNTEPVDD------IYCP 252

  Fly   561 PQSFLATKILQHIKEIIGPKGLFMLNLVCRD------ESLRTEALNNLHKVFPAVCSYKLEEDI- 618
            .......:.|.::.::||.||:...|:..:.      |.:|.:...:.|.     |.....:.:
Worm   253 VAPIRTPEFLDNLSKVIGTKGMTTFNVYIQKATIDNYERMRDDFSKHFHD-----CKLINSKHLL 312

  Fly   619 -NEIIYCANDEKY-------KT--------VEQWKKNM 640
             |..:.|:|...|       ||        :||:.:|:
Worm   313 ANMFLVCSNKGIYDNGVDVNKTKKFLRNMKIEQFLRNV 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2614	NP_610045.1	AdoMet_MTases	55..157	CDD:302624
CG2614	NP_610045.1	AdoMet_MTases	<483..>612	CDD:302624	33/141 (23%)
F52F12.9	NP_001021486.2	AdoMet_MTases	<153..>296	CDD:302624	39/148 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2352
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810