DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2614 and Y34B4A.7

DIOPT Version :9

Sequence 1:	NP_610045.1	Gene:	CG2614 / 35326	FlyBaseID:	FBgn0032873	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_508889.1	Gene:	Y34B4A.7 / 180793	WormBaseID:	WBGene00021323	Length:	369	Species:	Caenorhabditis elegans

Alignment Length:	438	Identity:	95/438 - (21%)
Similarity:	170/438 - (38%)	Gaps:	126/438 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   266 NEVIMDLHRPSEQTPRYTIHILDKPPARGLGKYAAFI---------------VPQGREVEWIFST 315
            ||::.:|.:|    || |:.:..|       :|.|||               :|    .|.:...
Worm    10 NEIVFNLKKP----PR-TMSLTTK-------RYFAFIFSFCIFMYLVLYFYVLP----AEVLVDE 58

  Fly   316 PAGR----------KKLQDSANFQRLAVVTLHRDQVYSTLD-EVKQELADSI-KNLSPAGLTDQI 368
            ..||          |.|::|...|..:.||   |..|..:| :|:.||...: :::...|..|:
Worm    59 QYGRGLDEELLNQKKGLEESIITQECSTVT---DNCYVVVDKKVETELGQMVERHMYVKGFEDE- 119

  Fly   369 PYLSLGSDVGKRETLICGFSKISGD----------FRIEEVEANGKTLRRLIFLSNQFVVQSEAL 423
                  ||...|  ||     ..||          ::::.:....:.:..||  |..|:|.|.:|
Worm   120 ------SDTIVR--LI-----PQGDRTFEYSDTRMWKVDHLSIRAQYIAALI--SAPFIVSSLSL 169

  Fly   424 VKTVKIKGKKDRKKIDFGYLACQHHLYMSVGVQLATTVQHPKRDVEKD---VLVVGLGGGGLCSF 485
            |                                          |.:.|   :|.:|||||.|..|
Worm   170 V------------------------------------------DSDNDGKAILEIGLGGGSLDMF 192

  Fly   486 LHAALPQARITAVEIDPIMLEVAEQYFELKQDKRFHVVIDDGLDFVERCRNEDIHFDAVLFDVDS 550
            ||...|:..||.||:||:::.:|.::|.:..|.....:..|||.|::..:.....::.|.  :|:
Worm   193 LHQLNPKLNITVVELDPVVVGIARKWFNVVNDNTRRTITADGLKFIKEAKKNGELYEVVF--LDA 255

  Fly   551 KDLSLGMSCPPQSFLATKILQHIKEIIGPKGLFMLNLVCRDESLR--TEALNNLHKVFPAVCSYK 613
            .|.|..:.||.:.|...:....:..|:...|..::|::.:::...  .:.:.:|.:.|.:.....
Worm   256 CDNSKIIPCPSKIFRNPETFSTLSSILSSTGALIVNILPQNDDTAGVIQIVEDLSQHFGSCIKVS 320

  Fly   614 LEEDINEIIYC---ANDEKYKTVEQWKK--NMGTAGRGLNSAVKETKL 656
            :.:::|.|..|   |..:....|:..|:  |..|...||...:|..|:
Worm   321 ITDEVNVIAICTKQAFTDSTSNVDFLKRRANAVTMRLGLQDVLKTIKI 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2614	NP_610045.1	AdoMet_MTases	55..157	CDD:302624
CG2614	NP_610045.1	AdoMet_MTases	<483..>612	CDD:302624	29/130 (22%)
Y34B4A.7	NP_508889.1	AdoMet_MTases	<177..359	CDD:302624	44/183 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2352
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4749
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D912165at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.770