Protein Alignment CG2614 and C01B10.8

DIOPT Version :9

• Sequence 1: NP_610045.1
• Gene: CG2614 / 35326
• FlyBaseID: FBgn0032873
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_501024.1
• Gene: C01B10.8 / 177431
• WormBaseID: WBGene00015282
• Length: 656
• Species: Caenorhabditis elegans
• Alignment Length: 670
• Identity: 229/670 - (34%)
• Similarity: 346/670 - (51%)
• Gaps: 65/670 - (9%)

  Fly     5 PKTREEFAQTDYWNEFFKKRGEKAFEWYGEYLELCDQIHKYIKPADRILMLGCGNSKLSMDMYDT 69
            |...:.|....||..||.|| :..|||||:|..|.:.|.||:||.|..|.||||||:|:..:||.
 Worm     4 PNEPQSFTDPAYWKNFFAKR-KSPFEWYGDYNSLSNVIDKYLKPKDTFLQLGCGNSELATQLYDN 67

  Fly    70 GFRDITNIDISPIAVKKMLELNAKSRPEMKFLQMDATAMTFPDESFSVSLDKGTLDALFADDEPE 134
            ||..|.:||:.|..:...:..| |.|..|.|...||..::..||:.::.:||||||||......|
 Worm    68 GFHCIHSIDVEPSVIATQIRKN-KERLGMTFETGDAANLSMADEAHTIVIDKGTLDALLPPSASE 131

  Fly   135 T-RAVVENYFKEILRTMRNGGRYVGISLLQEHILNFLLD-FLPKHNCMLRIVHCLGVEQANKEKN 197
            : .|:|...|:|:.|.:.:||||:.::|.|.||..|.:: |.|....:||:         .|.:|
 Worm   132 SDEALVTKMFEEVHRVLASGGRYIIVTLAQPHITEFWINHFYPLKQYILRV---------QKVEN 187

  Fly   198 ADDALTLPVFVVVATKFKS-----LPMPVLEFGFGNDKMQRFTTVSELNSAVSSVQKAA---LVC 254
            ......:|||..:|||.::     ||:.||.  ..:.:..|..:..||..::...|:.:   .:|
 Worm   188 KASGFPMPVFCFIATKMRAPMPNPLPLEVLR--SSSIRTDRIDSTDELKDSIRGEQELSQFIYLC 250

  Fly   255 NGLARSNIAGHNEVIMDLHRPSEQT-PRYTIHILDKPPARGLGKYAAFIVPQGREVEWIFSTPAG 318
            :....|      ||.:|.|...... |||.|.::|.|.|:.:..:|||:||.||:.||:|::|.|
 Worm   251 SKKLDS------EVSIDFHGADPSLGPRYRICVVDNPEAKKIDTFAAFVVPIGRDSEWLFASPKG 309

  Fly   319 RKKLQDSANFQRLAVVTLHRDQVYST-LDEVKQELADSIKNLSPAGLTD-------QIPYLSLGS 375
            ||.|:.....:|||:|.|:|:|.|.. :|.||.::...:      |:.|       ....||:|.
 Worm   310 RKALRVQCGRERLAIVFLNRNQKYEKGMDGVKSDIGHFV------GMLDVRQDNTGNYEILSIGG 368

  Fly   376 DVGKRETLICGFSKISGDFRIEEVEANGKTLRRLIFLSNQFVVQSEALVKTVKIKGKKDRKKIDF 440
             |..:.|:..|.|.|:|.:.:|||...|...|||:||:...:|||||.:||    |||.:..||.
 Worm   369 -VDVKRTVSTGRSDINGGWSVEEVTVEGNQTRRLVFLNTMNLVQSEAYLKT----GKKKQTVIDL 428

  Fly   441 GYLACQHHLYMSVGVQLATTVQHP--KRDVEKDVLVVGLGGGGLCSFLHAALPQARITAVEIDPI 503
            ..|||..| .|.:| .||.:.|.|  |.|.:..:.|:|||||.|.::|.....:|.:||||:||.
 Worm   429 DQLACDFH-RMMIG-SLAISPQQPLAKNDAQCKMAVLGLGGGLLTAYLVRHFKKAHVTAVELDPE 491

  Fly   504 MLEVAEQYFEL-KQDKRFHVVIDDGLDFVERC--RNEDIHFDAVLFDVDSKDLSLGMSCPPQSFL 565
            :|::|..:|.. ..|.|..|||.|.|..::..  :.|:..:|.:..|| |...:..:.|||.:||
 Worm   492 VLKIANSHFSFPHSDARIDVVIQDALIHLQETAKKPEEEKYDVIFVDV-SGSQNAALQCPPSAFL 555

  Fly   566 ATKILQHIKEIIGPKGLFMLNLVCRDESLRTEALNNLHKVFPAVCSYKLEEDINEIIYCANDEK- 629
            ..:.|.::|..:..:|:..||||.||.........|:.:.||.:.:....||:||||......|
 Worm   556 TPEALGNMKNSVKEQGMISLNLVTRDSEFGKSIKKNIAEYFPTLYTVLSFEDVNEIIIGLKTPKN 620

  Fly   630 -------YKTVEQWKKNMGT 642
                   .|.:...:|::|:
 Worm   621 TIKPVVPQKLINTVRKDIGS 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2614	NP_610045.1	AdoMet_MTases	55..157	CDD:302624	41/102 (40%)
		AdoMet_MTases	<483..>612	CDD:302624	40/131 (31%)
C01B10.8	NP_501024.1	AdoMet_MTases	44..>158	CDD:388410	46/114 (40%)
		Spermine_synth	337..572	CDD:334594	84/248 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167705
Domainoid	1	1.000	86	1.000	Domainoid score	I5183
eggNOG	1	0.900	-	-		E1_KOG2352
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H32285
Inparanoid	1	1.050	339	1.000	Inparanoid score	I1399
Isobase	1	0.950	-	0	Normalized mean entropy	S4749
OMA	1	1.010	-	-		QHG57818
OrthoDB	1	1.010	-	-		D373793at33208
OrthoFinder	1	1.000	-	-		FOG0006581
OrthoInspector	1	1.000	-	-		oto20197
orthoMCL	1	0.900	-	-		OOG6_100611
Panther	1	1.100	-	-	LDO	PTHR12176
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4655
SonicParanoid	1	1.000	-	-		X5580
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	16	15.790