Protein Alignment brun and Trappc9

DIOPT Version :9

• Sequence 1: NP_610044.2
• Gene: brun / 35325
• FlyBaseID: FBgn0261787
• Length: 1320
• Species: Drosophila melanogaster
• Sequence 2: XP_006521590.1
• Gene: Trappc9 / 76510
• MGIID: 1923760
• Length: 1148
• Species: Mus musculus
• Alignment Length: 1296
• Identity: 425/1296 - (32%)
• Similarity: 658/1296 - (50%)
• Gaps: 177/1296 - (13%)

  Fly    20 LSRPDYEQSALHHSCLLVLLRGVGPSRARVLQRAFEKVRRVNHIRVNDSSGHPRSIWIRFVHDHP 84
            :|.|||.|.|..|..|||:::.||........|.::::..|:.:.|.|:.   |:::||:.|.:|
Mouse     1 MSVPDYMQCAEDHQTLLVVVQAVGIVSEENFFRIYKRICSVSQLSVRDTQ---RALFIRYRHHYP 62

  Fly    85 VEHNDWGDFQTHRRLLGLVTIGKFDSQIELNELCRQHESLKVRYGSTLYESRAIFFGPDEQPLET 149
            .|:|:||||||||:::||:||....|..:..:...:....|..||||||:||...||..
Mouse    63 PENNEWGDFQTHRKVVGLITITDCFSPKDWPQTFEKFHVQKEIYGSTLYDSRLFVFGLQ------ 121

  Fly   150 IGEVLGPPAAGGRRLQDEFTTPSNFKAQAFFYREQDSCADLESRIGDFASALFWVLESRRLERSR 214
             |:|...|                 :....||...|.|..:|.||.||..:||.||||:||:|:.
Mouse   122 -GDVAEQP-----------------RPDVAFYPNYDDCDSVEKRIEDFIESLFIVLESKRLDRAT 168

  Fly   215 EKA-DKVSLLLAPFEKRDFVGLDMESRNNRKRCVGRVMKNLADLSLQAGLVDDALSLYHNANETL 278
            :|: ||:.||..||||:||||||.:||:.:|||.||:.|::.||.||||::.|||..||.:.|.|
Mouse   169 DKSGDKIPLLCVPFEKKDFVGLDTDSRHYKKRCQGRMRKHVGDLCLQAGMLQDALVHYHMSVELL 233

  Fly   279 RSVGDSLWVGATEEGLCAASAMLLYPQMRETETLHRNSSLQEAGTSPLKNTPEKWRASDATKKIS 343
            |||.|.||:||..||||:||.:..||                .||.          .....:::.
Mouse   234 RSVNDFLWLGAALEGLCSASVIYHYP----------------GGTG----------GKTGARRLQ 272

  Fly   344 ASDATANNVDSNQP-QQRVTSNSSSCSSVSSLVTTATNSSASDTPTTSSSSTSTISAAPIPGHQR 407
            .|...:...:.::| .|.|..:.      .:|.|...|      |.||:.    |..|.
Mouse   273 GSSLPSEAANRHRPGAQEVLIDP------GALTTNGIN------PDTSTE----IGRAK------ 315

  Fly   408 NGDLPGNILKAEEISNYYRKAIINYSKYRHAATIETEAALKASRICIEQNRPLDVAMFLQNILYI 472
                  |.|..|:|.:.|::||..||||::|..||.||.:||.|:...|.|.::.:.||||.:||
Mouse   316 ------NCLSPEDIIDKYKEAISYYSKYKNAGVIELEACVKAVRVLAIQKRGMEASEFLQNAVYI 374

  Fly   473 NL-SMSEAERVKRFEVITDLYQQIGYQRKAAFFQRLAALKHVQQGSQAPDWNQSYRLMLGSFTGY 536
            || .:||.|:::|:.::::||:.||:.||:|||:|:||::.|......|.|...|:|:|.:..||
Mouse   375 NLRQLSEEEKIQRYSILSELYELIGFHRKSAFFKRVAAMQCVAPSIAEPGWRACYKLLLETLPGY 439

  Fly   537 RLCLDPLEVIENA-AGWPALQIDLVQTLITAARRLGHSALATRHMTFLLQTQWDNMSPTEQSEMA 600
            .|.|||.:..:.. .||.|:|:.|:..|:.|:||:|:.||:.||::|||||..|.:|..|:.::.
Mouse   440 SLSLDPKDFSKGTHRGWAAVQMRLLHELVYASRRMGNPALSVRHLSFLLQTMLDFLSDQEKKDVT 504

  Fly   601 VQLQNLSAQCEGSPVPLVLENGTVIPPANLTDLPYCIDLQVKDLPAHLRPQRIKVAKADS----G 661
            ..|:|.:|:|.|:..|:.|.:|..:||...|.||....:::..||..|||.::|.....|    .
Mouse   505 QSLENYTAKCPGTMEPITLPDGLTLPPVPFTKLPIVRCVKLLSLPTSLRPHKVKSLLGQSMSTKS 569

  Fly   662 PFLFTPI--HFNSVDRRDKKKDKNKIAFQWVQNDLSEVTVRLRNPLPFELPVTDMRLLTNGVVFE 724
            ||:::||  | |..:.|:||.|     |||||.|:.||.:.:.||:||||.|.:|.|||:||.||
Mouse   570 PFIYSPIIAH-NRGEERNKKID-----FQWVQGDVCEVQLMVYNPMPFELRVENMGLLTSGVEFE 628

  Fly   725 SLPQTLVLQPHVPTY-VALHGTPIETGQLDLQGYSTHTLGVKSNCRLKHMRGRSFPPNYVVDVIP 788
            |||..|.|......| |.|.|.|..||.:.:.||.|...||.|:|.|.::.|.. .....|:|||
Mouse   629 SLPAALSLPAESGLYPVTLVGVPQTTGMITVNGYHTTVFGVFSDCLLDNLPGLK-TGGSTVEVIP 692

  Fly   789 ALPRISVKTSLPQTATFSNMNSADIVVTSASLTLYNGESSSCTITITNESATLPLEHLEFSINSN 853
            ||||:.:.||||::|.....::.|.:.|:.|:.|||||:....:|:.|.... |||.||.:....
Mouse   693 ALPRLQISTSLPRSARSLQPSAGDEIATNVSVQLYNGETQQLAVTLENIGLE-PLEQLEVTSKLL 756

  Fly   854 VEQE------LQQKIFRIDEEAIKAHLPVPPQGTIEIIVDVFAEADFVCPQPPASLHSAAAPGDY 912
            ..:|      |..|:    ||.: |..|:.|.......:::.|:.||.|.:  ..|...:..|
Mouse   757 TTKEKLYGDFLSWKL----EETL-AQFPLQPGKVATFTINIKAKLDFSCQE--NLLQDLSDDG-- 812

  Fly   913 GASSLTHYSSVSTSGHASLPSRVGSPHHRRNEPQNSSFRSTISGGPPSLAALTLHPGGGGGVGPS 977
                      :|.||.                |.:|.||..:.   |.:.:...:|..|...|
Mouse   813 ----------ISVSGF----------------PLSSPFRQVVR---PRVESRPTNPSEGSKTG-- 846

  Fly   978 SLGSQYNQHIEAQVRFKYSGGDALTAGYCRQCAVSFNLELLPSVQITSWDVLPAEVASQFYLVLD 1042
            .||  :.:.:||.:.||||||.....||.|..::..::|:.|||..|....|||....|.:|:||
Mouse   847 DLG--HVKTLEAVLNFKYSGGPGHVEGYYRNLSLGLHVEVEPSVFFTRVSTLPATSTRQCHLLLD 909

  Fly  1043 ISNLTAQEMSLNYTDTKNILIEAKESCRVPIPVDRCSLEKVVAARAAEVAENLERELCFRTQLLS 1107
            :.|.|..|:::...:...:::.|.|..|:.|.||:.:.|.|..:..         |......|..
Mouse   910 VFNSTEHELTVCARNNSELVLHASECQRMAIQVDKFNFESVPESPG---------EKGHFANLKQ 965

  Fly  1108 FNDALSKLCSIHIAERVKIKWLLTGTDIQGIASLRGIVLSQSMVDLTAVSPLEWAISFQDTLV-- 1170
            ..:...:...:.|:.::.|:|.:......|.||:.|: |:|.:::...::||:|     |.||
Mouse   966 LEEERQEARGLEISSKLDIRWRIPSLKRSGEASVEGL-LNQLILEHLQLAPLQW-----DVLVDG 1024

  Fly  1171 QPHN-EI--VCTVGQRSLLSIQLANQSLQPLRNLVLSIKFYQDYLNGMENYNLETRVAISGPNRI 1232
            ||.: |:  .|.||....|.::|.|:|.:.:....|::..:||:.||:.||:|...::..|.:..
Mouse  1025 QPCDCEVAAACQVGDPVRLEVRLTNRSPRSVGPFALTVVPFQDHQNGVHNYDLHDVISFVGSSTF 1089

  Fly  1233 AIPLLEKQEQKEHTC--SVIFFTPGRFKASIECTSNPQKQSEQPS-----SLLTRSCPAEA 1286
            .:..::...|.  ||  :::|...|.|..:|....:.:.:...||     |:..|:..|:|
Mouse  1090 YLDTVQPSGQS--TCLGALLFLYTGDFFLNIRFHEDCKSKELPPSWVCLPSVHVRALGAQA 1148

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
brun	NP_610044.2	TRAPPC9-Trs120	42..1238	CDD:285790	402/1217 (33%)
Trappc9	XP_006521590.1	TRAPPC9-Trs120	70..1102	CDD:370013	388/1176 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838638
Domainoid	1	1.000	126	1.000	Domainoid score	I5432
eggNOG	1	0.900	-	-		E1_KOG1953
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H81931
Inparanoid	1	1.050	599	1.000	Inparanoid score	I944
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG46678
OrthoDB	1	1.010	-	-		D36257at33208
OrthoFinder	1	1.000	-	-		FOG0004159
OrthoInspector	1	1.000	-	-		oto92037
orthoMCL	1	0.900	-	-		OOG6_105002
Panther	1	1.100	-	-	LDO	PTHR21512
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4122
SonicParanoid	1	1.000	-	-		X6103
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800