DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2611 and Zdhhc2

DIOPT Version :9

Sequence 1:	NP_610043.1	Gene:	CG2611 / 35324	FlyBaseID:	FBgn0032871	Length:	132	Species:	Drosophila melanogaster
Sequence 2:	NP_659564.3	Gene:	Zdhhc2 / 246326	RGDID:	628681	Length:	366	Species:	Rattus norvegicus

Alignment Length:	83	Identity:	17/83 - (20%)
Similarity:	22/83 - (26%)	Gaps:	47/83 - (56%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 PAMPGPVP--------WKTIIIILLLFIGGIVCIAFATLNWVTDTSRERSDRVWALGIIGALTFI 104
            |:.||.|.        |..::.|.||            |.|
  Rat     3 PSGPGGVRRRCRRVLYWIPVVFISLL------------LGW------------------------ 31

  Fly   105 PGSYYVYVL-FCIMLNRN 121
              |||.|.: .||:...|
  Rat    32 --SYYAYAIQLCIVSMEN 47

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2611	NP_610043.1	DUF872	<93..128	CDD:283547	7/30 (23%)
Zdhhc2	NP_659564.3	DHHC	19..301	CDD:418707	13/67 (19%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	297..366
		Mediates localization to plasma membrane and recycling endosomes. /evidence=ECO:0000250\|UniProtKB:P59267	298..366
		Non-canonical dileucine endocytic signal. /evidence=ECO:0000250\|UniProtKB:P59267	334..335
		NPxY-like endocytic signal. /evidence=ECO:0000250\|UniProtKB:P59267	357..360
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900