Protein Alignment CG2608 and SPAG7

DIOPT Version :10

• Sequence 1: NP_610042.1
• Gene: CG2608 / 35323
• FlyBaseID: FBgn0032870
• Length: 255
• Species: Drosophila melanogaster
• Sequence 2: NP_004881.2
• Gene: SPAG7 / 9552
• HGNCID: 11216
• Length: 227
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 87/238 - (36%)
• Similarity: 150/238 - (63%)
• Gaps: 20/238 - (8%)

  Fly     2 DLLDSILNAMDAPPANNEQQ-KTLIKKQREMLERMQNKQKEELLRFRKYVDERMGRFAKDDRRC- 64
            |||.|||::|:.||:..:|: :...::|...|:::|.::|::.:.|||.:::.:..|.:|..:.
Human     3 DLLGSILSSMEKPPSLGDQETRRKAREQAARLKKLQEQEKQQKVEFRKRMEKEVSDFIQDSGQIK 67

  Fly    65 IEFQPLDKVHRSVIHEVAENGGFIAMSFGREDVDRHSVVYKKEHAPGEDEVTARRNGDGWNEEIA 129
            .:|||::|:.||::|:|.|..|..:.|||.:|..|:.:::|||.||.::|:.:.|.|:.|:.:.|
Human    68 KKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRRGEEWDPQKA 132

  Fly   130 KEYAERRRERLAQEQSDKEASTSEAASSGSSTSTSADQDSGEVKPTTNYKAKYAHLIGESAALQA 194
            :|  :|:.:.|||.|.:      |||..|...          |.|.::||.||:||||:.||..|
Human   133 EE--KRKLKELAQRQEE------EAAQQGPVV----------VSPASDYKDKYSHLIGKGAAKDA 179

  Fly   195 ARKTETNQSYGFVPSKNKKDVRSIEQTLADIQAKKRLRLAQQQ 237
            |...:.|::||.||..||:|.||||:.:.:|:||||||.:.::
Human   180 AHMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLRQSGEE 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2608	NP_610042.1	R3H_sperm-antigen	47..106	CDD:100065	19/59 (32%)
SPAG7	NP_004881.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..46		14/42 (33%)
		Nuclear localization signal. /evidence=ECO:0000255	35..51		4/15 (27%)
		R3H_sperm-antigen	49..109	CDD:100065	19/59 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	118..160		15/59 (25%)
		Nuclear localization signal. /evidence=ECO:0000255	122..139		6/18 (33%)