DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2608 and Spag7

DIOPT Version :9

Sequence 1:	NP_610042.1	Gene:	CG2608 / 35323	FlyBaseID:	FBgn0032870	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_766149.2	Gene:	Spag7 / 216873	MGIID:	107380	Length:	227	Species:	Mus musculus

Alignment Length:	255	Identity:	92/255 - (36%)
Similarity:	155/255 - (60%)	Gaps:	34/255 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DLLDSILNAMDAPPANNEQQKTLIKKQREM---LERMQNKQKEELLRFRKYVDERMGRFAKDDRR 63
            |||.|||::|:.||:..:|:..  :|.||.   |:::|.:.|::.:.|||.:::.:..|.:|..:
Mouse     3 DLLGSILSSMEKPPSLGDQESR--RKAREQAARLKKLQEQDKQQKVEFRKRMEKEVSDFIQDSGQ 65

  Fly    64 C-IEFQPLDKVHRSVIHEVAENGGFIAMSFGREDVDRHSVVYKKEHAPGEDEVTARRNGDGWNEE 127
            . .:|||::|:.||::|:|.|..|..:.|||.:|..|:.:::|||.||.::|:.:.|:|:.|:.:
Mouse    66 VKKKFQPMNKIERSILHDVVEVAGLTSFSFGEDDDCRYVMIFKKEFAPSDEELDSYRHGEEWDPQ 130

  Fly   128 IAKEYAERRRERLAQEQSDKEASTSEAASSGSSTSTSADQDSGEVKPTTNYKAKYAHLIGESAAL 192
            .|:|  :|:.:.|||:|.:      |||..|.:.          |.|.::||.||:||||:.||.
Mouse   131 KAEE--KRKLKELAQKQEE------EAAQQGPAV----------VSPASDYKDKYSHLIGKGAAK 177

  Fly   193 QAARKTETNQSYGFVPSKNKKDVRSIEQTLADIQAKKRLRLAQQQELEQEQQAQEATTST 252
            .||...:.|::||.||..||:|.||||:.:.:|:||||||          |..:|..|::
Mouse   178 DAAHMLQANKTYGCVPVANKRDTRSIEEAMNEIRAKKRLR----------QSGEELPTTS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2608	NP_610042.1	R3H_sperm-antigen	47..106	CDD:100065	19/59 (32%)
Spag7	NP_766149.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45		16/43 (37%)
		Nuclear localization signal. /evidence=ECO:0000255	35..51		4/15 (27%)
		R3H_sperm-antigen	49..109	CDD:100065	19/59 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	118..161		16/60 (27%)
		Nuclear localization signal. /evidence=ECO:0000255	122..139		6/18 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833287
Domainoid	1	1.000	94	1.000	Domainoid score	I7492
eggNOG	1	0.900	-	-		E1_28PDV
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3595
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4200
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49694
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008421
OrthoInspector	1	1.000	-	-		oto95230
orthoMCL	1	0.900	-	-		OOG6_108973
Panther	1	1.100	-	-	LDO	PTHR13498
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5463
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790