Protein Alignment phr6-4 and PHR1

DIOPT Version :10

• Sequence 1: NP_477188.1
• Gene: phr6-4 / 35322
• FlyBaseID: FBgn0016054
• Length: 540
• Species: Drosophila melanogaster
• Sequence 2: NP_015031.1
• Gene: PHR1 / 854568
• SGDID: S000005913
• Length: 565
• Species: Saccharomyces cerevisiae
• Alignment Length: 532
• Identity: 135/532 - (25%)
• Similarity: 220/532 - (41%)
• Gaps: 130/532 - (24%)

  Fly     6 STLVHWFRKGLRLHDNPALSH---IFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWR--FLQ 65
            ||::||||..|||:||..|..   :|........|..:..:::::..  ||.....:.|:  |:.
Yeast    75 STVMHWFRNDLRLYDNVGLYKSVALFQQLRQKNAKAKLYAVYVINED--DWRAHMDSGWKLMFIM 137

  Fly    66 QTLEDLDNQLRKL-----------------NSRLFVVRGKPAEVFPRIFKSWRVE-----MLTFE 108
            ..|::|...|.:|                 ||:.||      |.|..  |...|.     ::|..
Yeast   138 GALKNLQQSLAELHIPLLLWEFHTPKSTLSNSKEFV------EFFKE--KCMNVSSGTGTIITAN 194

  Fly   109 TDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPIT-------------YQ 160
            .:.:...:.||.   :|.:.|..|::.    ..|:...::|..|    ||             |:
Yeast   195 IEYQTDELYRDI---RLLENEDHRLQL----KYYHDSCIVAPGL----ITTDRGTNYSVFTPWYK 248

  Fly   161 KFLGIVEQLKVPKV----LGVPEKLKNMPTPPKDEVEQKDSAAYDCP-TMKQLVKRPEELGPNKF 220
            |::..|...|....    |.:.|.||      .:|..:.....|..| ...|.:.:.:...|:.
Yeast   249 KWVLYVNNYKKSTSEICHLHIIEPLK------YNETFELKPFQYSLPDEFLQYIPKSKWCLPDV- 306

  Fly   221 PGGETEALRRMEESL----------KDEIWVARFEKPNTAPNSLEPSTTVLSPYLKFGCLSARLF 275
              .|..||.|:::.|          ||.:::.              .|:.||.|:..|.:|.||.
Yeast   307 --SEEAALSRLKDFLGTKSSKYNNEKDMLYLG--------------GTSGLSVYITTGRISTRLI 355

  Fly   276 -NQKLK----EIIKRQPKHSQPPVSLIGQLMWREFY--------YTVAAAEPNFDRMLGNVYCMQ 327
             ||..:    :|:.:..|.:....:.|.::.||:||        ||........|       .:.
Yeast   356 VNQAFQSCNGQIMSKALKDNSSTQNFIKEVAWRDFYRHCMCNWPYTSMGMPYRLD-------TLD 413

  Fly   328 IPWQEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFE 392
            |.|:.:|...|.|..|.||.|.:|||||:|...|:|::.:|...|.||:: :|.|.|..|:|.|.
Yeast   414 IKWENNPVAFEKWCTGNTGIPIVDAIMRKLLYTGYINNRSRMITASFLSK-NLLIDWRWGERWFM 477

  Fly   393 QLLLDQDWALNAGNWMWLSASAFFHQ-YFRVYSPVAFGKKTDPQGHYIRKYVPEL----SKYPAG 452
            :.|:|.|.:.|.|.|.:.|::....| ||||::.....||.|||..:::::||||    :|.|
Yeast   478 KHLIDGDSSSNVGGWGFCSSTGIDAQPYFRVFNMDIQAKKYDPQMIFVKQWVPELISSENKRP-- 540

  Fly   453 CIYEPWKASLVD 464
               |.:...|||
Yeast   541 ---ENYPKPLVD 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
phr6-4	NP_477188.1	PhrB	6..497	CDD:440184	135/532 (25%)
PHR1	NP_015031.1	PhrB	75..564	CDD:440184	135/532 (25%)