DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment phr6-4 and cry1

DIOPT Version :9

Sequence 1:	NP_001260632.1	Gene:	phr6-4 / 35322	FlyBaseID:	FBgn0016054	Length:	540	Species:	Drosophila melanogaster
Sequence 2:	NP_001017311.2	Gene:	cry1 / 550065	XenbaseID:	XB-GENE-946007	Length:	618	Species:	Xenopus tropicalis

Alignment Length:	494	Identity:	262/494 - (53%)
Similarity:	337/494 - (68%)	Gaps:	13/494 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VHWFRKGLRLHDNPALSHIFTAANAAPGKYFVRPIFILDPGILDWMQVGANRWRFLQQTLEDLDN 73
            ||||||||||||||||......|:.      :|.::||||.......||.||||||.|.|||||.
Frog     6 VHWFRKGLRLHDNPALRECIQGADT------IRCVYILDPWFAGSSNVGINRWRFLLQCLEDLDA 64

  Fly    74 QLRKLNSRLFVVRGKPAEVFPRIFKSWRVEMLTFETDIEPYSVTRDAAVQKLAKAEGVRVETHCS 138
            .||||||||||:||:||:||||:||.|::..|:.|.|.||:...||||::|||...||.|....|
Frog    65 NLRKLNSRLFVIRGQPADVFPRLFKEWKITKLSIEYDSEPFGKERDAAIKKLASEAGVEVIVRIS 129

  Fly   139 HTIYNPELVIAKNLGKAPITYQKFLGIV---EQLKVPKVLGVPEKLKNMPTPPKDEVEQKDSAAY 200
            ||:|:.:.:|..|.|:.|:||::|..::   |.|::|......|.::...||..|:.::|    |
Frog   130 HTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITAEVMEKCTTPVLDDHDEK----Y 190

  Fly   201 DCPTMKQLVKRPEELGPNKFPGGETEALRRMEESLKDEIWVARFEKPNTAPNSLEPSTTVLSPYL 265
            ..|::::|....|.|....:||||||||.|:|..|:.:.|||.||:|....|||..|||.|||||
Frog   191 GVPSLEELGFDTEGLPSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASTTGLSPYL 255

  Fly   266 KFGCLSARLFNQKLKEIIKRQPKHSQPPVSLIGQLMWREFYYTVAAAEPNFDRMLGNVYCMQIPW 330
            :|||||.|||..||.::.|:..|:|.||:||.|||:||||:||.|...|.||:|.||..|:||||
Frog   256 RFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPW 320

  Fly   331 QEHPDHLEAWTHGRTGYPFIDAIMRQLRQEGWIHHLARHAVACFLTRGDLWISWEEGQRVFEQLL 395
            ..:|:.|..|..||||:|:|||||.||||||||||||||||||||||||||||||||.:|||:||
Frog   321 DRNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELL 385

  Fly   396 LDQDWALNAGNWMWLSASAFFHQYFRVYSPVAFGKKTDPQGHYIRKYVPELSKYPAGCIYEPWKA 460
            ||.||::|||:|||||.|:||.|:|..|.||.||::|||.|.|||:|:|.|..:|...||:||.|
Frog   386 LDADWSVNAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPILKGFPPKYIYDPWNA 450

  Fly   461 SLVDQRAYGCVLGTDYPHRIVKHEVVHKENIKRMGAAYK 499
            ....|:...|::|.:||..:|.|....:.||:||...|:
Frog   451 PETVQKVAKCIIGVNYPKPMVNHAEASRLNIERMKQIYQ 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
phr6-4	NP_001260632.1	PhrB	5..499	CDD:223492	261/492 (53%)
phr6-4	NP_001260632.1	FAD_binding_7	297..496	CDD:377037	120/198 (61%)
cry1	NP_001017311.2	PhrB	6..491	CDD:223492	262/494 (53%)
cry1	NP_001017311.2	FAD_binding_7	288..486	CDD:377037	120/197 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	312	1.000	Domainoid score	I1292
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	586	1.000	Inparanoid score	I985
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D378952at2759
OrthoFinder	1	1.000	-	-		FOG0000663
OrthoInspector	1	1.000	-	-		otm47742
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X403
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.060