DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2493 and Dpp7

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_114179.1	Gene:	Dpp7 / 83799	RGDID:	71073	Length:	500	Species:	Rattus norvegicus

Alignment Length:	490	Identity:	190/490 - (38%)
Similarity:	272/490 - (55%)	Gaps:	38/490 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DMGEATVRAALLAVLGIL-LIAGCDCSQRFKYEIKEFQVPLDHFSF--LINATFNIRYLYNDSFV 66
            |.|..:....||..||:. |.|..|......:....|:..:|||:|  ..|.||..|:|.:|.|.
  Rat    10 DHGVPSWVLVLLLTLGLCSLQATADSVLDPDFRENYFEQYMDHFNFESFSNKTFGQRFLVSDKFW 74

  Fly    67 DKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPE 131
            .....  ||||||||||||...|.|:||:.|.|.:|.||::||||||||||||||..:......:
  Rat    75 KMGEG--PIFFYTGNEGDIWSLANNSGFIVELAAQQEALLVFAEHRYYGKSLPFGVQSTQRGYTQ 137

  Fly   132 HLAYFTVEQTLEDYAMLITFLRND---RQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPV 193
            .|   ||||.|.|:|:|:..||::   :..|.:||||||||||:|:.||||||||.|||||||||
  Rat   138 LL---TVEQALADFAVLLQALRHNLGVQDAPTIAFGGSYGGMLSAYMRMKYPHLVAGALAASAPV 199

  Fly   194 LQFPGITDCDIFYRIVTSVFQNAYNEN--CTLNIAKSWKLFETL---GASEAGKKQISDAFHLCN 253
            :...|:.:.|.|:|.||:.|   |.::  |...:..:::..:.|   ||.:.    ||..|..|.
  Rat   200 IAVAGLGNPDQFFRDVTADF---YGQSPKCAQAVRDAFQQIKDLFLQGAYDT----ISQNFGTCQ 257

  Fly   254 ALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSS 318
            :|.:..||.:...:....::.|||::|||.::||.||||.||:..|   :.|.|....::...:.
  Rat   258 SLSSPKDLTQLFGFARNAFTVLAMMDYPYPTNFLGPLPANPVKVGC---ERLLSEGQRIMGLRAL 319

  Fly   319 ALAVYTNYTQSAKCLDI--SVNSNADDSG---------WNIQSCNQMVMPICSNGSETMFRTSSW 372
            |..|| |.:....|.||  ...|.||.:|         |:.|:|.::.:...||....||....:
  Rat   320 AGLVY-NSSGMEPCFDIYQMYQSCADPTGCGTGSNARAWDYQACTEINLTFDSNNVTDMFPEIPF 383

  Fly   373 NFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIIL 437
            :.:...:.|...:.:.|:|..:...:.|.:|:||:|||||||.||||:|||:.:..:..:..:.:
  Rat   384 SDELRQQYCLDTWGVWPRPDWLQTSFWGGDLKAASNIIFSNGDLDPWAGGGIQRNLSTSIIAVTI 448

  Fly   438 PEGAHHLDLRHSDPADPPSVRDARDKEAAIIARWI 472
            ..||||||||.|:..|||||.:.|..||.:|..|:
  Rat   449 QGGAHHLDLRASNSEDPPSVVEVRKLEATLIREWV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	176/441 (40%)
Dpp7	NP_114179.1	Abhydrolase	48..475	CDD:304388	176/442 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55283
OrthoDB	1	1.010	-	-		D245747at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101877
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.730