DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2493 and AT5G22860

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_851059.1	Gene:	AT5G22860 / 832349	AraportID:	AT5G22860	Length:	502	Species:	Arabidopsis thaliana

Alignment Length:	461	Identity:	153/461 - (33%)
Similarity:	226/461 - (49%)	Gaps:	53/461 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 FQVPLDHFSFLINA--TFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQ 102
            |...||||:|...:  ||..||..:.:....:.|..||..:.|.|..::......|||.:...|.
plant    59 FNQTLDHFTFTPESYMTFQQRYAIDSTHWGGAKANAPILAFLGEESSLDSDLAAIGFLRDNGPRL 123

  Fly   103 RALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLR---NDRQMPVVAFG 164
            .||:::.||||||:::||||:.........|.|....|.|.|||.::..::   :....|::..|
plant   124 NALLVYIEHRYYGETMPFGSAEEALKNASTLGYLNAAQALADYAAILLHVKEKYSTNHSPIIVIG 188

  Fly   165 GSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSW 229
            ||||||||||||:||||:..||||:|||:|.|........:|.|||.||:.| :|.|...|..||
plant   189 GSYGGMLAAWFRLKYPHIALGALASSAPLLYFEDTRPKFGYYYIVTKVFKEA-SERCYNTIRNSW 252

  Fly   230 KLFETLGASEAGKKQISDAFHLCNALKNDDDLKKFLD--YVEEVYSNLAMVNYPYNSSFLAPLPA 292
            ...:.:.....|...:|..|..|..|....|:|.|||  |.|.|         .||..     |.
plant   253 IEIDRVAGKPNGLSILSKQFKTCAPLNGSFDIKDFLDTIYAEAV---------QYNRG-----PN 303

  Fly   293 YPVRQVCYYLKELHSTDAD--------LLHAMSSALAVYTNYTQSAKCLDISV-----NSNADDS 344
            :.|.:||      ::.:|:        |....:..:|:..|.|    |.|..:     |:|.
plant   304 FWVAKVC------NAINANPPNRRYNLLDRIFAGVVALVGNRT----CYDTKMFAQPTNNNI--- 355

  Fly   345 GWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRLTPKPYDIILRYGGRNLEA---- 405
            .|..|||:::|||:..:..:|||.|:.:|...|.:.|...:.:||:|:.|...:|.:.::.
plant   356 AWRWQSCSEIVMPVGYDKQDTMFPTAPFNMTSYIDGCKSYHGVTPRPHWITTYFGIQEVKLILQK 420

  Fly   406 -ATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAIIA 469
             .:||||||||.||:|.||||:..:|.:..|....|:|.||:......||..:...|:||..:|.
plant   421 FGSNIIFSNGLSDPYSVGGVLEDISDTLVAITTKNGSHCLDITLKSKEDPEWLVIQREKEIKVID 485

  Fly   470 RWIQDF 475
            .||..:
plant   486 SWISTY 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	147/445 (33%)
AT5G22860	NP_851059.1	Abhydrolase	61..480	CDD:389770	147/446 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2183
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55283
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3159
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11010
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3029
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.890