Protein Alignment CG2493 and Prss16

DIOPT Version :10

• Sequence 1: NP_610037.1
• Gene: CG2493 / 35316
• FlyBaseID: FBgn0032864
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_062302.1
• Gene: Prss16 / 54373
• MGIID: 1859181
• Length: 509
• Species: Mus musculus
• Alignment Length: 531
• Identity: 139/531 - (26%)
• Similarity: 210/531 - (39%)
• Gaps: 97/531 - (18%)

  Fly    11 VRAALLAVLGILLIAGCDCS----QRFKYEIKEFQ-------------------------VPLDH 46
            |:|..|..|.::.:.|....    :|.:..|::||                         .|||.
Mouse     3 VKAPWLGFLLLVSLWGLSTPALLLRRLREHIQKFQESSSLHPGFGLGHGPGAVPKQGWLEQPLDP 67

  Fly    47 FSFLINATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEH 111
            |:.....||..||..||.  .::....|:|.:.|.||.:...:...|.....|....||||..||
Mouse    68 FNASDRRTFLQRYWVNDQ--HRTGQDVPVFLHIGGEGSLGPGSVMAGHPAALAPAWGALVISLEH 130

  Fly   112 RYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYA----MLITFLRNDRQMPVVAFGGSYGGMLA 172
            |:||.|:|.|.  .:.:|   |.|.:....|.|.|    .|...|......|.:.|||||.|.||
Mouse   131 RFYGLSMPAGG--LDLAL---LRYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLA 190

  Fly   173 AWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVT-SVFQNAYNENCTLNIAKSWKLFET-- 234
            .|.|:|:||||..|:|:|||:   ..:.|...:.::|. |:.|.|...:.....|.|....|.
Mouse   191 TWARLKFPHLVFAAVASSAPL---SAVVDFSAYNQVVARSLTQVAIGGSLECLAAASTAFTEVER 252

  Fly   235 -LGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQV 298
             |.|..|.:..:.:....|.:|...:|..:.|..::.:......    |:....|||   .|||:
Mouse   253 LLRAGPAAQAVLREELGACGSLDLTEDQAELLGALQALVGGTVQ----YDGQAGAPL---SVRQL 310

  Fly   299 CYYL-----KELHSTD-ADLLHAMSSALAVYTNYTQSAKCLDIS--------VNSNADDSG---- 345
            |..|     ....||. ..|..|:...|.     :...|||..|        .|:....||
Mouse   311 CGLLLGKWGNRSRSTPYLGLRRAVQIVLR-----SMGQKCLSFSRAETVAQLSNTEPQVSGVGDR 370

  Fly   346 -WNIQSCNQMVMPICSNGSETMF-RTSSWNFKDYAEKCYKNYRLTP----------KPYDIILRY 398
             |..|:|.:....:...|.:..| :..:..|:  .|.|.:.:.|:|          ..|     |
Mouse   371 QWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQ--LELCEQVFGLSPASVAQAVAQTNSY-----Y 428

  Fly   399 GGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDK 463
            ||:: ..||.::|.||..|||....|.|........:::|..:|..|:....|:|.||:|..|.|
Mouse   429 GGQS-PGATQVLFVNGDTDPWHVLSVTQDLGLSEPALLIPSASHCFDMAPMRPSDSPSLRLGRQK 492

  Fly   464 EAAIIARWIQD 474
            .:..:..|::|
Mouse   493 ISQQLQDWLKD 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_610037.1	alpha/beta hydrolases	43..464	CDD:473884	127/458 (28%)
Prss16	NP_062302.1	Peptidase_S28	63..493	CDD:310284	127/459 (28%)