DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2493 and Prss16

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001028882.1	Gene:	Prss16 / 364719	RGDID:	1306652	Length:	512	Species:	Rattus norvegicus

Alignment Length:	526	Identity:	136/526 - (25%)
Similarity:	207/526 - (39%)	Gaps:	87/526 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VRAALLAVLGILLIAGCDCS----QRFKYEIKEFQ-------------------------VPLDH 46
            |:|..|..|.::.:.|....    :|.:..|:.||                         .|||.
  Rat     3 VKAPWLGFLLLVSLWGLSAPALLLRRLREHIQNFQESSNTHPGSVLGHGPGAIPKQGWLEQPLDP 67

  Fly    47 FSFLINATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEH 111
            |:......|..||..||.  .::....|:|.:.|.||.:...:..||.....|....||||..||
  Rat    68 FNATDRRIFLQRYWVNDQ--HRTGQDAPVFLHIGGEGSLGPGSVMTGHPAALAPAWGALVISLEH 130

  Fly   112 RYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYA----MLITFLRNDRQMPVVAFGGSYGGMLA 172
            |:||.|:|.|.  .:.:|   |.|.:....|.|.|    .|...|......|.:.|||||.|.||
  Rat   131 RFYGLSMPAGG--LDVAL---LHYLSSRHALADVASARQALSGLLNVSSSSPWICFGGSYAGSLA 190

  Fly   173 AWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVT-SVFQNAYNENCTLNIAKSWKLFET-- 234
            .|.|:|:||||..|:|:|||:   ..:.|...:.::|. |:.|.....:.....|.|....|.
  Rat   191 TWTRLKFPHLVFAAVASSAPL---NAVVDFSAYNQVVARSLTQVTIGGSLECLAAASTAFAEVER 252

  Fly   235 -LGASEAGKKQISDAFHLCNALKNDDDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQV 298
             |.|..|.:..:.:....|.:|...:|..:.|..::.:......    |:....:||   .|||:
  Rat   253 LLRAGLASQAVLREELGACGSLDLIEDQAELLGALQALVGGTVQ----YDGQAGSPL---SVRQL 310

  Fly   299 CYYL-----KELHSTD-ADLLHAMSSALAVYTNYTQSAKCLDIS-------------VNSNADDS 344
            |..|     ...|||. ..|..|:...|.     :...|||..|             ..|...|.
  Rat   311 CGLLLRTWGNRNHSTPYLGLRRAVQRVLR-----SMGQKCLSSSRAETVAQLRNTEPQVSGVGDR 370

  Fly   345 GWNIQSCNQMVMPICSNGSETMF-RTSSWNFKDYAEKCYKNYRLTPKPYDIILR-----YGGRNL 403
            .|..|:|.:....:...|.:..| :..:..|:  .:.|.:.:.|:|......:.     |||::
  Rat   371 QWLYQTCTEFGFYVTCEGLQCPFSQLPALPFQ--LDLCEQVFGLSPSSVAQAVAQTNSYYGGQS- 432

  Fly   404 EAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEAAII 468
            ..||.::|.||..|||....|.|........:::|..:|.||:....|:|.||:|..|.|....:
  Rat   433 PGATQVMFVNGDTDPWHVLSVTQDLGPSEPALLIPSASHCLDMAPMRPSDSPSLRLGRQKIFQQL 497

  Fly   469 ARWIQD 474
            ..|::|
  Rat   498 QVWLKD 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	124/453 (27%)
Prss16	NP_001028882.1	Peptidase_S28	63..493	CDD:253262	124/454 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920