DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2493 and Prcp

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_001099751.2	Gene:	Prcp / 293118	RGDID:	1307842	Length:	493	Species:	Rattus norvegicus

Alignment Length:	478	Identity:	212/478 - (44%)
Similarity:	288/478 - (60%)	Gaps:	14/478 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 MGEATVRAALLAVLGI--LLIAGCDCSQRFKYEIKEFQVPLDHFSFLINATFNIRYLYNDSFVDK 68
            :|.||.....|..||.  |.....|.:....|.:..||..:|||.|....||..|||..|....:
  Rat    14 LGAATTIRPRLKTLGSPHLSTNTPDPAVPSSYSVHYFQQKVDHFGFSDTRTFKQRYLVADKHWQR 78

  Fly    69 SNARTPIFFYTGNEGDIELFAQNTGFLWEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHL 133
            :..  .|.|||||||||..|..||||:|:.||..:|:::||||||||||||||..:|..|  :||
  Rat    79 NGG--SILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGKSLPFGRDSFKDS--QHL 139

  Fly   134 AYFTVEQTLEDYAMLITFLR----NDRQMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVL 194
            .:.|.||.|.|:|.||..|:    .....||:|.||||||||||||||||||:|.||||||||:.
  Rat   140 NFLTSEQALADFAELIRHLKETIPGTEGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIW 204

  Fly   195 QFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLFETLGASEAGKKQISDAFHLCNALKNDD 259
            |..|:..|..|.:|||..|..: ..:|:.:|.:||.:...|..:.:|.:.:.|..|||:.| ..:
  Rat   205 QLDGMAPCGEFMKIVTKDFSQS-GPHCSESIRRSWSVINRLSDTGSGLQWLRDTLHLCSPL-TSE 267

  Fly   260 DLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYT 324
            .:.....::.|.:.|||||||||..:||.||||:|:::||.||:..:.:|..||..:..||.||.
  Rat   268 KMPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCRYLRNPNVSDTVLLQNIFQALNVYY 332

  Fly   325 NYTQSAKCLDIS--VNSNADDSGWNIQSCNQMVMPICSNGSETMFRTSSWNFKDYAEKCYKNYRL 387
            ||:...|||:||  ..|:...:||:.|:|.:||||.|:||.:.||....|:.:.|:..|:..:.:
  Rat   333 NYSGQTKCLNISQTTTSSLGSTGWSFQACTEMVMPFCTNGIDDMFEPYLWDLETYSNDCFNQWGV 397

  Fly   388 TPKPYDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPA 452
            .|:|:.:...|||:|:.:.:|||||||.|||||||||.:...|.:..|.:||||||||||..:..
  Rat   398 KPRPHWMTTMYGGKNISSHSNIIFSNGDLDPWSGGGVTKDITDTLVAINIPEGAHHLDLRAHNAF 462

  Fly   453 DPPSVRDARDKEAAIIARWIQDF 475
            ||.||..:|..|...:.:||.||
  Rat   463 DPSSVLLSRLLEVKHMKKWIADF 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	196/426 (46%)
Prcp	NP_001099751.2	Abhydrolase	52..471	CDD:304388	195/424 (46%)
Prcp	NP_001099751.2	MhpC	101..>211	CDD:223669	65/111 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335257
Domainoid	1	1.000	388	1.000	Domainoid score	I767
eggNOG	1	0.900	-	-		E1_KOG2183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55867
Inparanoid	1	1.050	401	1.000	Inparanoid score	I1867
OMA	1	1.010	-	-		QHG55283
OrthoDB	1	1.010	-	-		D245747at33208
OrthoFinder	1	1.000	-	-		FOG0005023
OrthoInspector	1	1.000	-	-		oto96548
orthoMCL	1	0.900	-	-		OOG6_101877
Panther	1	1.100	-	-	LDO	PTHR11010
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3029
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770