DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2493 and pcp-4

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_507841.1	Gene:	pcp-4 / 180301	WormBaseID:	WBGene00003959	Length:	1042	Species:	Caenorhabditis elegans

Alignment Length:	462	Identity:	113/462 - (24%)
Similarity:	187/462 - (40%)	Gaps:	61/462 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 LDHFSFLINATFNIRYLYNDSFVDKSNARTPIFFYTGNEG--DIELFAQNTGFLWEQAERQRALV 106
            |||||......|..:|.|.:. :..||.:. .|.|...||  :|.:.......:.:.|:|..|.:
Worm    48 LDHFSNDSQVFFTQQYFYTER-LSVSNQKV-AFLYVNTEGNEEIAVMTDERSPVVKAAKRFGAQL 110

  Fly   107 IFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLRNDRQMPV----VAFGGSY 167
            ...:|||||.|.| ....|:.|.   |.|.|..|.::|....|.:......|..    |.:|..|
Worm   111 FALKHRYYGASKP-NFQNFDASA---LRYLTSRQAIQDILSFIKYANTQFNMNPDVRWVLWGTGY 171

  Fly   168 GGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIFYRIVTSVFQNAYNENCTLNIAKSWKLF 232
            ||:|||..|...|..|:||:::|||:.:   :.|...|...|.:........||...:.:.:...
Worm   172 GGILAAEARKTDPVAVSGAISSSAPLRR---LYDFWQFNDFVGNTLMQIGGSNCYGRVQQGFADI 233

  Fly   233 ETLGASEAGKKQISDAFHLCNALKND----DDLKKFLDYVEEVYSNLAMVNYPYNSSFLAPLPAY 293
            .....:.||:.||||.|.|...|...    :|::.|...:...:..:...|..:|.|
Worm   234 RQAMKTTAGRSQISDLFQLNPRLDQTQLGYNDIQMFYTAIIGPFQEIVQFNNDFNIS-------- 290

  Fly   294 PVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDIS-----VNSNADDS--------- 344
             :..:|..:.....|:.:::.  .:.:.:.|..|.|.:.:.|:     ||...:||
Worm   291 -ITDMCTIIANSSWTNMEVVR--QAYVYLSTTLTGSVQPMTIASYQKVVNDLKNDSVSSPFVENR 352

  Fly   345 GWNIQSCNQM-VMPICSNGSETMF----RTSSWNFKDYAEKC---YKNYRLTPKPY-DIILRYGG 400
            .|..|.|.:: ..|..:|..:.:|    .||.     |..:|   :.:..||.... |.|:  ..
Worm   353 MWTYQICTELGWFPTTNNNEQGLFGAVVPTSI-----YINQCSDIFPDASLTATSIRDSIV--SS 410

  Fly   401 RNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEGAHHLDLRHSDPADPPSVRDARDKEA 465
            .::...||::|:||..||||..|...:.:..|...::| ||.:|.......:|...::.|.|...
Worm   411 DSVYTGTNVVFTNGFYDPWSVLGQETSRDFSVVAYVIP-GASYLSDFFPGDSDNQYIQKAHDLMI 474

  Fly   466 AIIARWI 472
            ..|..|:
Worm   475 ENINIWV 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	111/452 (25%)
pcp-4	NP_507841.1	Abhydrolase	46..473	CDD:304388	111/452 (25%)
pcp-4	NP_507841.1	Peptidase_S28	552..980	CDD:253262
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920