DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2493 and pcp-2

DIOPT Version :9

Sequence 1:	NP_001260630.1	Gene:	CG2493 / 35316	FlyBaseID:	FBgn0032864	Length:	475	Species:	Drosophila melanogaster
Sequence 2:	NP_501599.1	Gene:	pcp-2 / 177741	WormBaseID:	WBGene00003957	Length:	1080	Species:	Caenorhabditis elegans

Alignment Length:	472	Identity:	120/472 - (25%)
Similarity:	192/472 - (40%)	Gaps:	59/472 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 YEIKEFQVPLDHFSFLINATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIE---LFAQNTGFL- 95
            :|...|:...|||:......|..|:..|..:.....   |.|...|.||..:   :..:|..:|
Worm   574 FETGSFRQRQDHFNNQNADFFQQRFFKNTQWAKPGG---PNFLMIGGEGPDKASWVLNENLPYLI 635

  Fly    96 WEQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLRNDRQMPV 160
            |  |::..|.|...|||:||:|....::.||     .|:...:...:.|:...:. :::....|.
Worm   636 W--AKKYGATVYMLEHRFYGESRVGDNTNFN-----RLSSLQMIYDIADFIRSVN-IKSGTSNPW 692

  Fly   161 VAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDCDIF-YRIVTSVFQNAYNENCTLN 224
            :.|||||.|:::||.|..:|.||.||:|:||||     ....|.: |.:|......:||..|...
Worm   693 ITFGGSYSGLISAWTREVFPELVVGAVASSAPV-----FAKTDFYEYLMVAENSIRSYNSTCADR 752

  Fly   225 IAKSWKLFETLGASEAGKKQISDAFHLCNAL-KNDDDLKKFLDYVEEVYSNL-AMVNY------P 281
            |.:.:.....|..::.|::.:|..|.|.... .|..|:.:.. :...:|||. ..|.|      .
Worm   753 IQEGFNSMRALFLTKGGRQTLSSMFKLDPPFADNVTDIDQHY-FFSNIYSNFQGDVQYSGDNMGS 816

  Fly   282 YNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYTQSAKCLDISVNS------N 340
            |.:|       |.:..:|..:....:|..:.:.|.:..:|.:.|.......||.|...      |
Worm   817 YANS-------YGIPDMCKIMTNDSNTPLNNIVAFNEYMANFYNGGGPYFGLDNSYQDMINFLIN 874

  Fly   341 ADDSG--------WNIQSCNQM-VMPICSNGSETMFRTSSWNF-----KDYAEKCYKNYRLTPKP 391
            |.|.|        |..|:|::. ......:|:......:..||     .|.....|:...:.|..
Worm   875 AKDFGPDAEASLLWTWQTCSEFGYFQSADSGNGIFGSPTPVNFFIQICMDVFNNYYQRSAIDPMV 939

  Fly   392 YDIILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDKVFVIILPEG-AHHLDLRHSDPADPP 455
            .:....||.|.....:|::|.||..|||...| |..|.|...|..|.:| ||..|:..:..||.|
Worm   940 DNTNYMYGERFHFRGSNVVFPNGNKDPWHALG-LYYPTDSSVVSYLIDGTAHCADMYPARDADVP 1003

  Fly   456 SVRDARDKEAAIIARWI 472
            .::..||.....||.|:
Worm  1004 GLKVVRDLIDQNIAIWL 1020

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	115/454 (25%)
pcp-2	NP_501599.1	Abhydrolase	50..476	CDD:304388
pcp-2	NP_501599.1	Peptidase_S28	581..1012	CDD:253262	115/455 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D555765at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920