Protein Alignment CG2493 and pcp-5

DIOPT Version :9

• Sequence 1: NP_001260630.1
• Gene: CG2493 / 35316
• FlyBaseID: FBgn0032864
• Length: 475
• Species: Drosophila melanogaster
• Sequence 2: NP_001367399.1
• Gene: pcp-5 / 176111
• WormBaseID: WBGene00022801
• Length: 507
• Species: Caenorhabditis elegans
• Alignment Length: 475
• Identity: 183/475 - (38%)
• Similarity: 273/475 - (57%)
• Gaps: 46/475 - (9%)

  Fly    32 RFKYEIKEFQVPLDHFSFLINATFNIRYLYNDSFVDKSNARTPIFFYTGNEGDIELFAQNTGFLW 96
            ::|||....:.|:|.|:|..:..|::||..|   :|......||.|||||||.:|.||:||||:|
 Worm    38 KYKYEEGYLKAPIDPFAFTNDLEFDLRYFLN---IDHYETGGPILFYTGNEGSLEAFAENTGFMW 99

  Fly    97 EQAERQRALVIFAEHRYYGKSLPFGSSTFNTSLPEHLAYFTVEQTLEDYAMLITFLRNDR----- 156
            :.|...:|.|:|.|||:||||.||.:.:: |.: .||.|.:.:|.|.|:|:.:.|.:|::
 Worm   100 DLAPELKAAVVFVEHRFYGKSQPFKNESY-TDI-RHLGYLSSQQALADFALSVQFFKNEKIKGAQ 162

  Fly   157 QMPVVAFGGSYGGMLAAWFRMKYPHLVNGALAASAPVLQFPGITDC----DIFYRIVTSVFQNAY 217
            :..|:||||||||||:||||:||||:|:||:||||||..|   ||.    |::..|||..|.:|
 Worm   163 KSAVIAFGGSYGGMLSAWFRIKYPHIVDGAIAASAPVFWF---TDSNIPEDVYDFIVTRAFLDA- 223

  Fly   218 NENCTLN-IAKSWKLFETLGASEAGKKQISDAFHL--CNALKNDDDLKKFLDYVEEVYSNLAMVN 279
              .|... |.|.|...:.|..|::|::.::..:.|  .:.|:|.||:.....|:.|....:||||
 Worm   224 --GCNRKAIEKGWIALDELAKSDSGRQYLNVLYKLDPKSKLENKDDIGFLKQYIRESMEAMAMVN 286

  Fly   280 YPYNSSFLAPLPAYPVRQVCYYLKELHSTDADLLHAMSSALAVYTNYT--------QSAKCLDIS 336
            |||.:|||:.|||:||::.|....:...|..:....:...:.:|.|||        .:||| |.:
 Worm   287 YPYPTSFLSSLPAWPVKEACKSASQPGKTQEESAEQLYKIVNLYYNYTGDKSTHCANAAKC-DSA 350

  Fly   337 VNSNADDSGWNIQSCNQMVMPICSNG--SETMFRTSSWNFKDYAEKCYKNY------RLTPKPYD 393
            ..|..|..||..|:|.:||||:|.:|  ::..::...:..:.|||.|.:.:      :...:|..
 Worm   351 YGSLGDPLGWPFQTCTEMVMPLCGSGYPNDFFWKDCPFTSEKYAEFCMQTFSSIHYNKTLLRPLA 415

  Fly   394 IILRYGGRNLEAATNIIFSNGLLDPWSGGGVLQAPNDK----VFVIILPEGAHHLDLRHSDPADP 454
            ..|.:|..:|.:|:||:||||.||||||||  ...:||    |..:||.:||||.|||.:.|.|.
 Worm   416 GGLAFGATSLPSASNIVFSNGYLDPWSGGG--YDHSDKVQGSVISVILKQGAHHYDLRGAHPQDT 478

  Fly   455 PSVRDARDKEAAIIARWIQD 474
            ..|:..|..|...|.:||::
 Worm   479 EEVKKVRAMETQAIKKWIKE 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2493	NP_001260630.1	Abhydrolase	43..464	CDD:304388	176/452 (39%)
pcp-5	NP_001367399.1	Peptidase_S28	48..488	CDD:310284	176/453 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156552
Domainoid	1	1.000	304	1.000	Domainoid score	I752
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55867
Inparanoid	1	1.050	319	1.000	Inparanoid score	I1499
Isobase	1	0.950	-	0	Normalized mean entropy	S5188
OMA	1	1.010	-	-		QHG55283
OrthoDB	1	1.010	-	-		D245747at33208
OrthoFinder	1	1.000	-	-		FOG0005023
OrthoInspector	1	1.000	-	-		otm14206
orthoMCL	1	0.900	-	-		OOG6_101877
Panther	1	1.100	-	-	LDO	PTHR11010
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2714
SonicParanoid	1	1.000	-	-		X3029
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	15	14.890