Protein Alignment Cdc23 and ALA1

DIOPT Version :10

• Sequence 1: NP_610036.2
• Gene: Cdc23 / 35315
• FlyBaseID: FBgn0032863
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_014980.3
• Gene: ALA1 / 854513
• SGDID: S000005862
• Length: 958
• Species: Saccharomyces cerevisiae
• Alignment Length: 237
• Identity: 45/237 - (18%)
• Similarity: 85/237 - (35%)
• Gaps: 82/237 - (34%)

  Fly   111 SYMAREKRRLDSTTDQANLHEP---------NQMR------------DLADLLATLRMEYGKSRL 154
            |.:|.||.|.|.:..:|..:|.         .|::            |||..:..:|..:|::..
Yeast   623 SLVAPEKLRFDFSHKKAVSNEELKKVEDICNEQIKENLQVFYKEIPLDLAKSIDGVRAVFGETYP 687

  Fly   155 DGYGIYLYGVVLKALNLNQAAEQMLVQAIRLVPMLWSAYLELSPLIMEKKKLLSLQL-GGHWMRH 218
            |...:...|..::.|..|.|.|:            |:.|              |::. ||
Yeast   688 DPVRVVSVGKPIEELLANPANEE------------WTKY--------------SIEFCGG----- 721

  Fly   219 FFMAHTYLELYLNDDG-LKIYEDLQASGFSKSIYLIAQMALVYHNKRDVDKAIELYQALLESDPY 282
                     .::|..| :|.:..|:.||.:|.|..|..:.           ..|.::|...::.:
Yeast   722 ---------THVNKTGDIKYFVILEESGIAKGIRRIVAVT-----------GTEAFEAQRLAEQF 766

  Fly   283 RLDNVDTYSNLLF-------VKEMKTEMAQLAHKAVSINKYR 317
            ..| :|....|.|       :||:..::.||:...::.|:.:
Yeast   767 AAD-LDAADKLPFSPIKEKKLKELGVKLGQLSISVITKNELK 807

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc23	NP_610036.2	ANAPC8	13..119	CDD:427675	4/7 (57%)
		LapB	255..521	CDD:442196	11/70 (16%)
		TPR repeat	255..278	CDD:276809	2/22 (9%)
		TPR repeat	318..346	CDD:276809	45/237 (19%)
		TPR repeat	351..381	CDD:276809
		TPR repeat	386..414	CDD:276809
		TPR repeat	420..448	CDD:276809
		TPR repeat	454..477	CDD:276809
		TPR repeat	494..522	CDD:276809
ALA1	NP_014980.3	PLN02900	7..946	CDD:215487	45/237 (19%)