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Protein Alignment Cdc23 and cdc27

DIOPT Version :10

Sequence 1:	NP_610036.2	Gene:	Cdc23 / 35315	FlyBaseID:	FBgn0032863	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_001072470.1	Gene:	cdc27 / 779925	XenbaseID:	XB-GENE-972658	Length:	832	Species:	Xenopus tropicalis

Alignment Length:	506	Identity:	111/506 - (21%)
Similarity:	207/506 - (40%)	Gaps:	110/506 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 RRLDSTTDQANLHEPNQMRDLADLLATLRMEYGKSRLDGYGIYLYGVV------LKALNLNQAAE 176
            |:..|.|.:..:.:.| |.|..::          |:||. .|...|.:      ::||.:.:||.
Frog   407 RKTKSKTSKGGVTQAN-MNDSLEI----------SKLDS-SIISEGKISSVAPQIQALTIQKAAA 459

  Fly   177 QMLVQAIRLVPMLWSAYLELSPLIMEKKKLLSLQLGGHWMRHFFMAHTYLEL--YLNDDGLKIYE 239
            :.|:..:|                                   .|...|:.|  |...:.:.|..
Frog   460 EGLMSLLR-----------------------------------DMGKGYVALCSYNCKEAINILS 489

  Fly   240 DLQASGFSKSIYLIAQMALVYHNKRDVDKAIELYQALLESDPYRLDNVDTYSNLLFVKEMKTEMA 304
            .|.:..::.. :::.|:...|....:..:|..::..:...:.||::.::.||..|:..:....::
Frog   490 HLPSHHYNTG-WVLCQIGRAYFELAEYLQAERVFSEVRRIESYRVEGMEIYSTTLWHLQKDVTLS 553

  Fly   305 QLAHKAVSINKYRPETCCVIGNYYSIRCDHQVAISYFQRALKLNPKYLAAWTLMGHEFMELKNTN 369
            .|:.....::|..||..|..||.:|::.:|.:||.:||||::::|.|..|:||:||||:..:..:
Frog   554 VLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPGYAYAFTLLGHEFVLTEELD 618

  Fly   370 AAIQSYRKAVEVNKRDYRAWYGLGQAYEIIKMHYYSL--YYFKIAHQLRPYDSRMLVALGETYEK 432
            .|:..:|.|:.||.|.|.||||||..|  .|...:||  .:|:.|..:.|..|.:|..:|.....
Frog   619 KALACFRNAIRVNPRHYNAWYGLGMIY--YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHA 681

  Fly   433 LDKCENAVKCYWKAIDVGDIEGIAMYKLANL---HEKLGDHETAVHCYIMYCEDERAATDKQSLY 494
            |.|.:.|:....|||.:.....:..:..|::   :||   ::.|    :...|:.:....|:||.
Frog   682 LKKSDKALDTLNKAISIDPKNPLCKFHRASILFANEK---YKLA----LQELEELKQIVPKESLV 739

  Fly   495 QGFITLANYYEKKGEYERAAYYAYKCLDSEDRKMEAKALLKTIDW-----KRNAEGQKKVKTSTA 554
              :..:...|:|.|:...|                    |....|     .:.|..|.|    .|
Frog   740 --YFLIGKVYKKLGQTHLA--------------------LMNFSWAMDLDPKGANNQIK----EA 778

  Fly   555 VANADTSSEDEMEWELQDVRVRVPITSIATTTTSTTTV---------AAES 596
            :.......::|...:.:.:....|..|:||..:..:::         ||||
Frog   779 IDKRYLPDDEEAVTQEEQISECYPYESVATDESQESSMTDADDTQLHAAES 829

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.