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Protein Alignment Cdc23 and cdc27

DIOPT Version :10

Sequence 1:	NP_610036.2	Gene:	Cdc23 / 35315	FlyBaseID:	FBgn0032863	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	XP_073791995.1	Gene:	cdc27 / 30450	ZFINID:	ZDB-GENE-990706-2	Length:	837	Species:	Danio rerio

Alignment Length:	461	Identity:	107/461 - (23%)
Similarity:	201/461 - (43%)	Gaps:	61/461 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 RRLDSTTDQANLHEPNQMRDLADLLATLRMEYGKSRLDGYGIYLYGVVLKALNLNQAAEQMLVQA 182
            |:..:.|.:..: .|:.:.:..::|     :...|..:|.| .:.....:|.||.:||...|:..
Zfish   417 RKTKTKTGKGGI-TPSNLNESIEIL-----KLDSSLSEGKG-NISSPQFQAFNLQKAAADGLMTL 474

  Fly   183 IRLVPMLWSAYLEL-SPLIMEKKKLLSLQLGGHWMRHFFMAHTYLELYLNDDGLKIYEDLQASGF 246
            :|   .:...||.| |....|...:|| ||..|   |:
Zfish   475 MR---DIGRGYLALCSYNCREAINILS-QLPSH---HY--------------------------- 505

  Fly   247 SKSIYLIAQMALVYHNKRDVDKAIELYQALLESDPYRLDNVDTYSNLLFVKEMKTEMAQLAHKAV 311
             .:.:::.|:...:....:..:|..::..:...:.||::.:|.||..|:..:....::.|:....
Zfish   506 -NTGWVLGQIGRAHFELAEYMQAERIFSEVRRIESYRVEGMDIYSTTLWHLQKDVALSALSKDLT 569

  Fly   312 SINKYRPETCCVIGNYYSIRCDHQVAISYFQRALKLNPKYLAAWTLMGHEFMELKNTNAAIQSYR 376
            .::|..||..||:||.:|::.:|.:||.:|.||::::|.:..|:||:|||.:..:....|:..:|
Zfish   570 DMDKNSPEPWCVVGNCFSLQREHDIAIKFFTRAIQVDPSFAYAYTLLGHELVLTEELEKALGCFR 634

  Fly   377 KAVEVNKRDYRAWYGLGQAYEIIKMHYYSL--YYFKIAHQLRPYDSRMLVALGETYEKLDKCENA 439
            .|:.:|||.|.||||||..|  .|...::|  .:||.|..:.|..|.:|..:|.....|.|.::|
Zfish   635 NAIRLNKRHYNAWYGLGMIY--YKQEKFNLAEIHFKKAFSINPQSSVLLCHIGVVQHALKKSDHA 697

  Fly   440 VKCYWKAIDVGDIEGIAMYKLANL---HEKLGDHETAVHCYIMYCEDERAATDKQSLYQGFITLA 501
            ::...:||.:.....:..:..|::   :||   ::.|    :...|:.:....|:||.  :..:.
Zfish   698 LETLNRAISIDPKNPLCKFHRASILFANEK---YKAA----LQELEELKQIVPKESLV--YFLIG 753

  Fly   502 NYYEKKGEYERAAYYAYKCLDSEDRKMEAKALLKTIDWKRNAEGQKKVKTSTAVANADTSSEDEM 566
            ..|:|.|:...|.......:|. |.|.....:.:.|| ||......:..|........|..|:..
Zfish   754 KVYKKLGQTHLALMNFSWAMDL-DPKGANNQIKEAID-KRYLPDDDEPVTPDDYPYCSTEVEESQ 816

  Fly   567 EWELQD 572
            |..:.|
Zfish   817 ESSMTD 822

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.