DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc2 and Arpc2

DIOPT Version :9

Sequence 1:	NP_001286102.1	Gene:	Arpc2 / 35311	FlyBaseID:	FBgn0032859	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001344316.1	Gene:	Arpc2 / 76709	MGIID:	1923959	Length:	300	Species:	Mus musculus

Alignment Length:	297	Identity:	225/297 - (75%)
Similarity:	260/297 - (87%)	Gaps:	0/297 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MILLEINNRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYK 65
            |||||:|||||||||.:|:.||.||.|||::::..||||||||||||.|||||||.:||||||||
Mouse     1 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYK 65

  Fly    66 QLQEHGADELLKREYGSLLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRNCFASVFEKYFD 130
            :||.|||||||||.|||.|.:.|.|||||:|.:||.:|...:.|..:.|:||||||||||||||.
Mouse    66 ELQAHGADELLKRVYGSFLVNPEPGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQ 130

  Fly   131 YQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELREGRRASHTA 195
            :||:|:||:.||||:||:|||:|||:|.|||||||||:|:|:|||:||||||||.:|||||||||
Mouse   131 FQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTA 195

  Fly   196 PQVLFSHREPPLELANTDARVGDNIGYVTFVLFPRHTNKETRDNTINLIHMFRDYLHYHIKCSKA 260
            ||||||||||||||.:|||.|||||||:||||||||||...|||||||||.||||||||||||||
Mouse   196 PQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNATARDNTINLIHTFRDYLHYHIKCSKA 260

  Fly   261 YIHSRMRAKTSDFLKVLNRARPEPKNTEKKTITGRTF 297
            |||:||||||||||||||||||:.:..|.|||||:||
Mouse   261 YIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc2	NP_001286102.1	P34-Arc	57..284	CDD:397935	176/226 (78%)
Arpc2	NP_001344316.1	P34-Arc	57..284	CDD:367780	176/226 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831957
Domainoid	1	1.000	373	1.000	Domainoid score	I889
eggNOG	1	0.900	-	-		E1_COG4690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4187
Inparanoid	1	1.050	471	1.000	Inparanoid score	I1495
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54321
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004402
OrthoInspector	1	1.000	-	-		oto93416
orthoMCL	1	0.900	-	-		OOG6_102851
Panther	1	1.100	-	-	LDO	PTHR12058
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R88
SonicParanoid	1	1.000	-	-		X3120
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.790