DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc2 and arpc2

DIOPT Version :9

Sequence 1:	NP_001286102.1	Gene:	Arpc2 / 35311	FlyBaseID:	FBgn0032859	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_997864.1	Gene:	arpc2 / 327068	ZFINID:	ZDB-GENE-030131-5276	Length:	299	Species:	Danio rerio

Alignment Length:	299	Identity:	221/299 - (73%)
Similarity:	264/299 - (88%)	Gaps:	0/299 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MILLEINNRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYK 65
            |||||||||||||||.:|:.:|..|.|||::::..||||||||||||.|||||||.:||||||:|
Zfish     1 MILLEINNRIIEETLSLKFDSASNGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFFK 65

  Fly    66 QLQEHGADELLKREYGSLLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRNCFASVFEKYFD 130
            :||||||||||||.||:.|...|:|||:|:|.:|:.:|.:.|::..:.|:||||||||||||||.
Zfish    66 ELQEHGADELLKRVYGNFLVAPEDGYNISLLFDLDALPPNKEEMIHQAGILKRNCFASVFEKYFK 130

  Fly   131 YQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELREGRRASHTA 195
            :||:|.:|:||||::||:||::|:|||.|||||||||:|:|:||||||||||||.:|||||||||
Zfish   131 FQEEGRDGEKRAVVHYRDDESMYIEAKKDRVTVVFSTVFKDDDDVIIGKVFMQEFKEGRRASHTA 195

  Fly   196 PQVLFSHREPPLELANTDARVGDNIGYVTFVLFPRHTNKETRDNTINLIHMFRDYLHYHIKCSKA 260
            ||||||||||||||.:|||.|||||||:||||||||||..||||||||||.||||||||||||||
Zfish   196 PQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNANTRDNTINLIHTFRDYLHYHIKCSKA 260

  Fly   261 YIHSRMRAKTSDFLKVLNRARPEPKNTEKKTITGRTFKR 299
            |||:||||||||||||||||||:.:..|.|||:|:||.|
Zfish   261 YIHTRMRAKTSDFLKVLNRARPDAEKKEMKTISGKTFSR 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc2	NP_001286102.1	P34-Arc	57..284	CDD:397935	173/226 (77%)
arpc2	NP_997864.1	P34-Arc	57..284	CDD:281970	173/226 (77%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574809
Domainoid	1	1.000	373	1.000	Domainoid score	I846
eggNOG	1	0.900	-	-		E1_COG4690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4187
Inparanoid	1	1.050	467	1.000	Inparanoid score	I1501
OMA	1	1.010	-	-		QHG54321
OrthoDB	1	1.010	-	-		D1345377at2759
OrthoFinder	1	1.000	-	-		FOG0004402
OrthoInspector	1	1.000	-	-		oto39950
orthoMCL	1	0.900	-	-		OOG6_102851
Panther	1	1.100	-	-	LDO	PTHR12058
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R88
SonicParanoid	1	1.000	-	-		X3120
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800