DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc2 and Arpc2

DIOPT Version :9

Sequence 1:	NP_001286102.1	Gene:	Arpc2 / 35311	FlyBaseID:	FBgn0032859	Length:	301	Species:	Drosophila melanogaster
Sequence 2:	NP_001100389.1	Gene:	Arpc2 / 301511	RGDID:	1305848	Length:	300	Species:	Rattus norvegicus

Alignment Length:	297	Identity:	225/297 - (75%)
Similarity:	260/297 - (87%)	Gaps:	0/297 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MILLEINNRIIEETLLVKYRNAQAGLKPESIDIRIADFDGVLYHISNVNGDKTKVRISISLKFYK 65
            |||||:|||||||||.:|:.||.||.|||::::..||||||||||||.|||||||.:||||||||
  Rat     1 MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYK 65

  Fly    66 QLQEHGADELLKREYGSLLTDTEEGYNVSVLINLEEIPEDCEQIAKRIGLLKRNCFASVFEKYFD 130
            :||.|||||||||.|||.|.:.|.|||||:|.:||.:|...:.|..:.|:||||||||||||||.
  Rat    66 ELQAHGADELLKRVYGSFLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQ 130

  Fly   131 YQEQGEEGQKRAVINYRNDETLYVEAKPDRVTVVFSTIFRDEDDVIIGKVFMQELREGRRASHTA 195
            :||:|:||:.||||:||:|||:|||:|.|||||||||:|:|:|||:||||||||.:|||||||||
  Rat   131 FQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTA 195

  Fly   196 PQVLFSHREPPLELANTDARVGDNIGYVTFVLFPRHTNKETRDNTINLIHMFRDYLHYHIKCSKA 260
            ||||||||||||||.:|||.|||||||:||||||||||...|||||||||.||||||||||||||
  Rat   196 PQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNATARDNTINLIHTFRDYLHYHIKCSKA 260

  Fly   261 YIHSRMRAKTSDFLKVLNRARPEPKNTEKKTITGRTF 297
            |||:||||||||||||||||||:.:..|.|||||:||
  Rat   261 YIHTRMRAKTSDFLKVLNRARPDAEKKEMKTITGKTF 297

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc2	NP_001286102.1	P34-Arc	57..284	CDD:397935	176/226 (78%)
Arpc2	NP_001100389.1	P34-Arc	57..284	CDD:397935	176/226 (78%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335631
Domainoid	1	1.000	373	1.000	Domainoid score	I860
eggNOG	1	0.900	-	-		E1_COG4690
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4187
Inparanoid	1	1.050	470	1.000	Inparanoid score	I1461
OMA	1	1.010	-	-		QHG54321
OrthoDB	1	1.010	-	-		D1345377at2759
OrthoFinder	1	1.000	-	-		FOG0004402
OrthoInspector	1	1.000	-	-		oto96958
orthoMCL	1	0.900	-	-		OOG6_102851
Panther	1	1.100	-	-	LDO	PTHR12058
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3120
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770