DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and slc3a2a

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_571676.2	Gene:	slc3a2a / 796322	ZFINID:	ZDB-GENE-000831-3	Length:	485	Species:	Danio rerio

Alignment Length:	299	Identity:	61/299 - (20%)
Similarity:	100/299 - (33%)	Gaps:	85/299 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 VSEELCYNRWKKLRDRFGREFRSHQINQSTPITWRYFND--------LLFLGRHFRKGVPLVLE- 234
            |.|:|.|....|::........|.|.:||:.:.....|.        ...|.|..|||:.:||:
Zfish   128 VEEKLDYLSQMKVKGLVLGPVHSVQADQSSALELTSINPDFGSESELTSLLDRAHRKGISIVLDL 192

  Fly   235 NIKRRGRPPKAGNPSGKTSKQPEGMVISSGEQIW---GADYPYSTDNDDLEDDL----------- 285
            ....||......|.:....|..:..|      .|   |.|..:.:|.:|:.:..
Zfish   193 TPNYRGVSSWFNNAASVAEKLKKACV------YWLNKGVDGIFLSDLNDIVNTYAWSSIQAIFNK 251

  Fly   286 --------------ELAYDEEIEILSEAE-----QATPYDFILS--EATARQDL-EPPQQLQV-- 326
                          .|:.||...:|:::.     ...||...||  :||..|.| ...|:..:
Zfish   252 TDGTPKKALMGTASSLSVDETSLLLNQSGVDLLLTKLPYPAGLSGRQATLMQRLCSGHQEASLGW 316

  Fly   327 ---------TTTTPATSEEIIHTIARVNPVVEESSSLPGDSVPSAAISDKLLTTVIANMETVLQQ 382
                     .:.|||...::..|:.         .:|||..|.||  .|:|          .|:.
Zfish   317 GLGQTAGSQASRTPALPVKLYQTLL---------FALPGTPVFSA--GDEL----------GLKA 360

  Fly   383 SRELQAQIHHEQEQERE--QRSTQPANSLLAKAQMLLDG 419
            ...:...::...|:||.  :...:..:.|..|.:.||.|
Zfish   361 GEAMWEDVNSTAEEERTAVRNFFKTLSDLKGKERSLLHG 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	12/54 (22%)
slc3a2a	NP_571676.2	SLC3A2_N	42..111	CDD:292647
		AmyAc_SLC3A2	94..396	CDD:200483	58/294 (20%)
		AmyA	125..445	CDD:223443	61/299 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900