DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and zgc:152938

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001070756.1	Gene:	zgc:152938 / 768145	ZFINID:	ZDB-GENE-061013-458	Length:	292	Species:	Danio rerio

Alignment Length:	234	Identity:	48/234 - (20%)
Similarity:	89/234 - (38%)	Gaps:	61/234 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   139 EQLIELVKSHPVLYDRHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKLRDRFGREFRSHQ 203
            |.||.||.....|:|::.|.. |::..:...|:||:|.:....:....:||.|||.:.|:.|..|
Zfish    58 EGLISLVSDRRELFDQNHIDY-KHIDKREALWQEIAEKIGFHVDDVKTKWKNLRDTYIRKKREDQ 121

  Fly   204 -INQSTP---ITWRYFNDLLFL----------------------GRHFRKGVPLVLENIKRRGRP 242
             ..:.||   .||::...:.||                      |....|.:.:.:|:.. ...|
Zfish   122 CTGEQTPKKKKTWKFMKMMEFLATSSEQRRVHSSVKESADEVGDGSESEKSLSISVESAV-SSEP 185

  Fly   243 PKAGNPSGKTSKQPEGMVISSGEQIWGADYPYSTDNDD-----LEDDLELAYDEEIEILSEAEQA 302
            .:|.:...|.|..|:.:     |:...|......:.::     :|||:.|
Zfish   186 VQANSKKRKRSVTPDFV-----EKYLAAKEVRDREREECRKQRMEDDISL--------------- 230

  Fly   303 TPYDFILSEATARQDLEPPQQLQVTTTTPATSEEIIHTI 341
                |::|.|...:.|.|.:|    ::......:::|.:
Zfish   231 ----FLMSLAPVIRRLPPSKQ----SSVKMRFHQVLHEV 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	27/111 (24%)
zgc:152938	NP_001070756.1	MADF_DNA_bdg	60..128	CDD:287510	20/68 (29%)
zgc:152938	NP_001070756.1	BESS	226..260	CDD:281011	9/56 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1634040at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010