DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and SLC3A1

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_000332.2	Gene:	SLC3A1 / 6519	HGNCID:	11025	Length:	685	Species:	Homo sapiens

Alignment Length:	163	Identity:	30/163 - (18%)
Similarity:	50/163 - (30%)	Gaps:	67/163 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 AWREISENLNVSEELCYNRW----------KKLRDRFGREFRSHQIN---------QSTPITWRY 214
            :|.|     |:.|    .:|          .:|..|.|.::    :|         ..||||  |
Human   430 SWME-----NMPE----GKWPNWMIGGPDSSRLTSRLGNQY----VNVMNMLLFTLPGTPIT--Y 479

  Fly   215 FNDLLFLGRHFRKGVPLVLENIKR-------RGRPPKAGNPSGKTSKQPEGMVISSGEQIW-GAD 271
            :.:.:.:|.       :|..|:..       |.:.|...:.|....       .|.....| ..:
Human   480 YGEEIGMGN-------IVAANLNESYDINTLRSKSPMQWDNSSNAG-------FSEASNTWLPTN 530

  Fly   272 YPYSTDNDDLE-----------DDLELAYDEEI 293
            ..|.|.|.|::           .||.|.:..|:
Human   531 SDYHTVNVDVQKTQPRSALKLYQDLSLLHANEL 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	15/75 (20%)
SLC3A1	NP_000332.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..56
SLC3A1	NP_000332.2	AmyAc_SLC3A1	116..569	CDD:200494	30/163 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900