DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and Adf1

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001260730.1	Gene:	Adf1 / 47082	FlyBaseID:	FBgn0284249	Length:	274	Species:	Drosophila melanogaster

Alignment Length:	338	Identity:	81/338 - (23%)
Similarity:	135/338 - (39%)	Gaps:	79/338 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 DSQDDLLNEQ----LIELVKSHPVLYDRHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKL 191
            |..|..|.:|    |||.||.:||:|||..... |:...|.:.|::|:|.|.|.|:.|..|||.|
  Fly     2 DKLDANLEQQFDLNLIEAVKLNPVIYDRSHYNY-KHFVRKAQTWKQIAETLGVPEQKCTKRWKSL 65

  Fly   192 RDRFGREFRSHQINQSTPITWRYFNDLLFLG---RHFRKGVPLVLENIKRRGRPPKAGNPSGKTS 253
            ||:|.||.:..|.::     ||||..:.||.   |.:|:.:.....|..:...  :..:||.:..
  Fly    66 RDKFAREMKLCQESR-----WRYFKQMQFLVDSIRQYRESLLGKCANGSQSAN--QVADPSQQQQ 123

  Fly   254 KQPEGMVISSGEQIWGADYPYSTDNDDLEDDLELAYDEEIEILSEAEQAT-------PYDFILSE 311
            .|.:.:|....:...|:    :|.:..     .|.:..||.:.|:|:.||       ||.:
  Fly   124 AQQQTVVDIFAQPFNGS----ATTSAQ-----ALTHPHEITVTSDAQLATAVGKDQKPYFY---- 175

  Fly   312 ATARQDLEPPQQLQVTTTTPATSEEIIHTIARVNPVVEESSSLPGDSVPSAAISDKLLTTVIANM 376
                   |||  |:...:....|:.:::||......|.::.|          ..|:....|:.:|
  Fly   176 -------EPP--LKRERSEEEHSDNMLNTIKIFQNNVSQAVS----------AEDQSFGMVVTDM 221

  Fly   377 ETVLQQSRELQAQIHHEQEQEREQRSTQPANSLLAKAQMLLDGLSPSERASAERKIVQFLCQCQI 441
            ...|...::.:|::|              ....|...|:|...... ......|:::|.|
  Fly   222 LNTLGVRQKAEAKVH--------------IIKYLTDMQLLAQHNKYXLSGGCHRQLLQLL----- 267

  Fly   442 KALDGEEIEDVAP 454
                  ::|.|.|
  Fly   268 ------QLESVLP 274

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	37/92 (40%)
Adf1	NP_001260730.1	MADF	15..95	CDD:214738	35/85 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438475
Domainoid	1	1.000	62	1.000	Domainoid score	I10337
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1634040at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm49873
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850