DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and CG12768

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_001262229.1	Gene:	CG12768 / 40513	FlyBaseID:	FBgn0037206	Length:	429	Species:	Drosophila melanogaster

Alignment Length:	346	Identity:	76/346 - (21%)
Similarity:	126/346 - (36%)	Gaps:	86/346 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 SQDDLLNEQLIELVKSHPVLYD---RHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKLRD 193
            |:.::...:|||||:.:|:|:|   .|..|..|..|.|   |.|:....||:.|.....:..||:
  Fly     4 SRHNIEKRRLIELVRLNPILWDCRLPHYKRSDKRKAIK---WNELGRLFNVNGERVQRTFTSLRE 65

  Fly   194 RFGREFRSHQINQSTPI--TWRYFNDLLFLGRHFRK-------------GVPLVLENIKRRGR-- 241
            .|.||....::..:|..  .|.|::.:.||....|:             ..|:...:......
  Fly    66 IFRRELNHEKMLGTTRFKSKWEYYDAMAFLKEVIRERKSRERIKHGSLDSAPVATGSSNNNNNCV 130

  Fly   242 ---------------------PPKAGNPSGKTSKQPEGMVISSGEQIWGADYPYSTDNDDLE-DD 284
                                 |....||:.:...|||..          :..|.:..:..|. ..
  Fly   131 SRNSSNNNSSSAALDEYQYFAPSDPNNPNNQPQLQPEPK----------SSLPVTIPSLSLTLSQ 185

  Fly   285 LELAYDEEIEILSEAEQATPYDFILSEATARQDLEPPQQLQVTTTTPATSEEIIHTIARVNPVVE 349
            |.:|..::.:.| :|.|..| |..|   |:.|....|..|  |..|||       .:|:.:|...
  Fly   186 LPVALQQQAQHL-QALQLQP-DVTL---TSLQKQSLPTSL--TNATPA-------PLAQTSPAQV 236

  Fly   350 ESSSLPGDSVPSAAISDKLLTTVIANMETVL-----QQSRELQAQIHHEQEQEREQR-------- 401
            .|||....|.||..|.|:..:......|.|:     :.:|:..|.|..:.:|:.:.|
  Fly   237 LSSSRSCSSSPSIYIKDEPCSPAGGCPEEVMTGNGPEATRKKLATIRPQTKQQLKARLQLPTPKN 301

  Fly   402 ----STQPANSLLAKAQMLLD 418
                :|.|.:.::.....|:|
  Fly   302 SSSYATSPPHLIINANNELID 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	28/90 (31%)
CG12768	NP_001262229.1	MADF	12..100	CDD:214738	28/90 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438461
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840