DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10949 and slc3a2b

DIOPT Version :9

Sequence 1:	NP_001286101.1	Gene:	CG10949 / 35310	FlyBaseID:	FBgn0032858	Length:	459	Species:	Drosophila melanogaster
Sequence 2:	NP_958922.2	Gene:	slc3a2b / 399488	ZFINID:	ZDB-GENE-040122-2	Length:	504	Species:	Danio rerio

Alignment Length:	148	Identity:	32/148 - (21%)
Similarity:	55/148 - (37%)	Gaps:	35/148 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   145 VKSHPVLY----DRHKIRVSKNLAAKNEAWREISENLNVSEELCYNRWKKLRDRFGREF-----R 200
            |..:|.:.    |..|   .|.::..:..::.:|........|.:..:..|   |..:|     |
Zfish   376 VNKYPTMLWKFNDEEK---QKEMSTYHSFFKSVSVKRMKERSLQHGEYLPL---FNSDFAMAYVR 434

  Fly   201 SHQINQSTPITWRYFNDLLFLGRHFRKGVPLVLENIKRRGRPPKAG---NPSGKTSKQPE----G 258
            |...|:      ||   |:.|..|..:.|.|   .:|....|..|.   :.||:|....|    .
Zfish   435 SWDQNE------RY---LIALNWHSNETVSL---QLKHADIPESATVVFSTSGETEVNKELNLAQ 487

  Fly   259 MVISSGEQIWGADYPYST 276
            :.::.||.|. ..:||::
Zfish   488 LEVNPGEGIM-LKFPYTS 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10949	NP_001286101.1	MADF	5..91	CDD:214738
CG10949	NP_001286101.1	MADF	140..226	CDD:214738	18/89 (20%)
slc3a2b	NP_958922.2	SLC3A2_N	49..119	CDD:292647
		AmyAc_SLC3A2	103..415	CDD:200483	6/41 (15%)
		AmyA	133..471	CDD:223443	23/112 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0366
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900